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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB1
All Species:
15.76
Human Site:
S25
Identified Species:
24.76
UniProt:
Q9Y478
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y478
NP_006244.2
270
30382
S25
K
T
P
R
R
D
S
S
G
G
T
K
D
G
D
Chimpanzee
Pan troglodytes
XP_513749
272
30341
G25
A
A
R
S
E
G
A
G
G
H
A
P
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
G25
A
A
R
S
E
G
A
G
G
H
A
P
G
K
E
Dog
Lupus familis
XP_543421
270
30281
S25
K
T
P
R
R
D
S
S
G
G
A
K
D
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9R078
270
30290
S25
K
T
P
R
R
D
S
S
G
G
A
K
D
G
D
Rat
Rattus norvegicus
P80386
270
30376
S25
K
T
P
R
R
D
S
S
G
G
T
K
D
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
L40
T
H
W
R
P
S
G
L
R
F
P
Q
R
G
P
Chicken
Gallus gallus
NP_001035001
273
30440
A27
R
G
D
G
A
G
G
A
G
S
T
K
D
G
D
Frog
Xenopus laevis
NP_001085572
266
29829
P36
A
K
I
L
M
D
S
P
E
D
A
D
M
F
P
Zebra Danio
Brachydanio rerio
NP_001002632
268
30343
K25
R
R
D
S
R
G
T
K
E
G
D
R
P
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610460
341
36399
S101
Y
T
G
T
G
T
G
S
T
R
R
G
T
A
H
Honey Bee
Apis mellifera
XP_393160
283
31818
A39
S
P
G
K
E
G
Q
A
F
V
F
D
K
K
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
S25
P
T
K
E
S
M
S
S
S
F
D
F
K
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
S59
H
S
P
R
A
T
Q
S
P
L
M
F
A
P
Q
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
P30
M
S
D
V
R
E
K
P
S
N
A
Q
G
C
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.5
70.9
98.5
N.A.
96.6
96.3
N.A.
63.8
91.2
80.3
81.1
N.A.
43.9
50.1
N.A.
49.4
Protein Similarity:
100
82.3
82.3
98.8
N.A.
97.7
98.5
N.A.
71.9
94.8
87.7
89.6
N.A.
54.8
66
N.A.
65.2
P-Site Identity:
100
6.6
6.6
93.3
N.A.
93.3
100
N.A.
13.3
40
13.3
13.3
N.A.
13.3
0
N.A.
20
P-Site Similarity:
100
20
20
93.3
N.A.
93.3
100
N.A.
20
53.3
13.3
33.3
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.8
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.7
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
14
0
0
14
0
14
14
0
0
40
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
20
0
0
34
0
0
0
7
14
14
34
0
34
% D
% Glu:
0
0
0
7
20
7
0
0
14
0
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
7
14
7
14
0
7
0
% F
% Gly:
0
7
14
7
7
34
20
14
47
34
0
7
20
40
7
% G
% His:
7
7
0
0
0
0
0
0
0
14
0
0
0
0
7
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
27
7
7
7
0
0
7
7
0
0
0
34
14
27
0
% K
% Leu:
0
0
0
7
0
0
0
7
0
7
0
0
0
0
0
% L
% Met:
7
0
0
0
7
7
0
0
0
0
7
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
7
7
34
0
7
0
0
14
7
0
7
14
7
7
20
% P
% Gln:
0
0
0
0
0
0
14
0
0
0
0
14
0
0
7
% Q
% Arg:
14
7
14
40
40
0
0
0
7
7
7
7
7
0
0
% R
% Ser:
7
14
0
20
7
7
40
47
14
7
0
0
0
0
0
% S
% Thr:
7
40
0
7
0
14
7
0
7
0
20
0
7
7
0
% T
% Val:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _