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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSC22D4
All Species:
8.48
Human Site:
Y268
Identified Species:
26.67
UniProt:
Q9Y3Q8
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Q8
NP_112197.1
395
41026
Y268
R
P
S
S
P
A
L
Y
F
T
H
D
A
S
L
Chimpanzee
Pan troglodytes
XP_519260
395
41108
Y268
R
P
S
S
P
A
L
Y
F
A
H
D
A
S
L
Rhesus Macaque
Macaca mulatta
XP_001118117
246
25347
S145
P
T
P
Q
S
G
L
S
Q
G
P
T
S
W
L
Dog
Lupus familis
XP_536862
395
40861
Y268
R
P
G
S
P
A
L
Y
L
F
P
D
A
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQN3
387
39969
A260
D
S
R
P
N
S
P
A
L
Y
F
D
A
S
L
Rat
Rattus norvegicus
NP_001037749
387
40022
A260
D
S
R
P
N
S
P
A
L
Y
F
D
A
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91012
1040
105912
E897
L
P
Q
A
A
S
G
E
S
S
V
G
A
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956403
556
58684
P407
I
D
E
G
L
R
K
P
E
M
L
Q
Q
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
59.2
87.5
N.A.
84.3
85.3
N.A.
N.A.
22.3
N.A.
31.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
59.7
89.6
N.A.
88
89.1
N.A.
N.A.
28.4
N.A.
41.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
73.3
N.A.
26.6
26.6
N.A.
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
20
73.3
N.A.
33.3
33.3
N.A.
N.A.
40
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
13
38
0
25
0
13
0
0
75
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
13
0
0
0
0
0
0
0
0
0
63
0
0
13
% D
% Glu:
0
0
13
0
0
0
0
13
13
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
25
13
25
0
0
0
0
% F
% Gly:
0
0
13
13
0
13
13
0
0
13
0
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% K
% Leu:
13
0
0
0
13
0
50
0
38
0
13
0
0
0
75
% L
% Met:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
50
13
25
38
0
25
13
0
0
25
0
0
0
0
% P
% Gln:
0
0
13
13
0
0
0
0
13
0
0
13
13
0
0
% Q
% Arg:
38
0
25
0
0
13
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
25
25
38
13
38
0
13
13
13
0
0
13
88
13
% S
% Thr:
0
13
0
0
0
0
0
0
0
13
0
13
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
0
0
0
0
0
0
38
0
25
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _