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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSC22D4 All Species: 7.27
Human Site: S69 Identified Species: 22.86
UniProt: Q9Y3Q8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3Q8 NP_112197.1 395 41026 S69 S P P P G A P S S R F R V V K
Chimpanzee Pan troglodytes XP_519260 395 41108 S69 S P P P G A P S S R F R V V K
Rhesus Macaque Macaca mulatta XP_001118117 246 25347
Dog Lupus familis XP_536862 395 40861 A69 S P P P G A P A S R F R V V K
Cat Felis silvestris
Mouse Mus musculus Q9EQN3 387 39969 A69 S P P P G A P A S R F R V V K
Rat Rattus norvegicus NP_001037749 387 40022 A69 S P P P G A P A S R F R V V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q91012 1040 105912 P671 P A A A P A Q P V A H A P A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956403 556 58684 S135 S A T V S T C S S R F R V I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 59.2 87.5 N.A. 84.3 85.3 N.A. N.A. 22.3 N.A. 31.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 59.7 89.6 N.A. 88 89.1 N.A. N.A. 28.4 N.A. 41.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 93.3 N.A. 93.3 93.3 N.A. N.A. 6.6 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. N.A. 6.6 N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 13 13 0 75 0 38 0 13 0 13 0 13 13 % A
% Cys: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % F
% Gly: 0 0 0 0 63 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 63 63 63 13 0 63 13 0 0 0 0 13 0 0 % P
% Gln: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 75 0 75 0 0 0 % R
% Ser: 75 0 0 0 13 0 0 38 75 0 0 0 0 0 0 % S
% Thr: 0 0 13 0 0 13 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 13 0 0 0 0 13 0 0 0 75 63 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _