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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK6
All Species:
41.82
Human Site:
Y111
Identified Species:
76.67
UniProt:
Q9Y3D8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3D8
NP_001015891.1
172
20061
Y111
E
R
L
E
T
R
G
Y
N
E
K
K
L
T
D
Chimpanzee
Pan troglodytes
XP_001145727
104
12543
E55
L
K
D
N
I
Q
C
E
I
F
Q
V
L
Y
E
Rhesus Macaque
Macaca mulatta
XP_001093722
171
20047
Y110
E
R
L
E
T
R
G
Y
N
E
K
K
L
T
D
Dog
Lupus familis
XP_535264
290
32045
Y229
K
R
L
E
T
R
G
Y
N
E
K
K
L
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCP8
172
19929
Y111
K
R
L
E
T
R
G
Y
N
E
K
K
L
Q
D
Rat
Rattus norvegicus
Q5EB68
172
19926
Y111
K
R
L
E
T
R
G
Y
H
E
K
K
L
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512366
172
20206
Y112
K
R
L
E
S
R
G
Y
S
E
K
K
L
Q
D
Chicken
Gallus gallus
NP_001026504
171
20053
Y111
D
R
L
E
S
R
G
Y
K
G
K
K
L
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002118
171
19818
Y111
N
R
L
E
S
R
G
Y
T
G
K
K
L
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394153
177
20763
Y116
D
R
L
R
D
R
G
Y
T
G
K
K
L
E
D
Nematode Worm
Caenorhab. elegans
Q09527
182
21006
Y119
D
R
L
Q
S
R
G
Y
S
E
F
K
I
K
E
Sea Urchin
Strong. purpuratus
XP_799000
161
18783
Y101
H
R
L
E
Q
R
G
Y
S
G
R
K
L
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12055
197
22705
Y116
S
R
L
H
A
R
G
Y
H
D
S
K
I
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.6
95.3
53
N.A.
87.7
86
N.A.
79
77.3
N.A.
75
N.A.
N.A.
55.3
45.5
54.6
Protein Similarity:
100
56.9
96.5
57.2
N.A.
94.7
93
N.A.
91.2
90.6
N.A.
88.3
N.A.
N.A.
72.3
67.5
72.6
P-Site Identity:
100
6.6
100
86.6
N.A.
86.6
80
N.A.
73.3
66.6
N.A.
66.6
N.A.
N.A.
60
46.6
60
P-Site Similarity:
100
33.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
80
N.A.
73.3
N.A.
N.A.
66.6
86.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
8
0
8
0
0
0
0
8
0
0
0
0
77
% D
% Glu:
16
0
0
70
0
0
0
8
0
54
0
0
0
24
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
93
0
0
31
0
0
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
0
0
16
0
0
% I
% Lys:
31
8
0
0
0
0
0
0
8
0
70
93
0
16
0
% K
% Leu:
8
0
93
0
0
0
0
0
0
0
0
0
85
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
31
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
8
0
0
0
0
8
0
0
39
0
% Q
% Arg:
0
93
0
8
0
93
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
0
0
31
0
0
0
24
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
39
0
0
0
16
0
0
0
0
16
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _