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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED31 All Species: 41.82
Human Site: Y66 Identified Species: 61.33
UniProt: Q9Y3C7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3C7 NP_057144.1 131 15805 Y66 K D P E Y A K Y L K Y P Q C L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103338 125 15272 Y60 K D P E Y A K Y L K Y P Q C L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CXU1 131 15753 Y66 K E P E Y A K Y L K Y P Q C L
Rat Rattus norvegicus NP_001129285 131 15772 Y66 K E P E Y A K Y L K Y P Q C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521735 355 37889 Y290 K E P E Y A K Y L K Y P Q C L
Chicken Gallus gallus XP_415924 124 15200 Y60 K E P E Y A K Y L K Y P Q C L
Frog Xenopus laevis Q4QR03 128 15701 Y63 K E P E Y A K Y L K Y P Q C L
Zebra Danio Brachydanio rerio Q6DH26 136 16502 F63 K E P E Y A K F L K Y P H C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IH24 204 23512 Y70 K E P D Y A K Y L M Y P M C L
Honey Bee Apis mellifera XP_393244 156 18762 Y83 K E P E Y A K Y L K Y P M C L
Nematode Worm Caenorhab. elegans P91869 163 19459 C59 K D P Q Y A R C L K F P Q C L
Sea Urchin Strong. purpuratus XP_794567 223 25980 Y76 K E P N Y A K Y L K F P Q C L
Poplar Tree Populus trichocarpa XP_002321780 191 22032 F68 Q R P E Y M K F I M Y P H C L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYB1 196 22801 F80 Q R P E Y I K F I M Y P H C L
Baker's Yeast Sacchar. cerevisiae P38633 127 14722 C72 C N P P Y S Q C I V Y P N C L
Red Bread Mold Neurospora crassa Q7SF81 134 15245 Y82 S R P P Y L K Y I T Y P G P T
Conservation
Percent
Protein Identity: 100 N.A. 95.4 N.A. N.A. 97.7 97.7 N.A. 36.6 90.8 90.8 82.3 N.A. 44.6 59.6 47.8 43.5
Protein Similarity: 100 N.A. 95.4 N.A. N.A. 100 99.2 N.A. 36.9 92.3 94.6 87.5 N.A. 55.8 69.8 61.3 51.1
P-Site Identity: 100 N.A. 100 N.A. N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 80 N.A. 73.3 86.6 73.3 80
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 100 100 100 93.3 N.A. 86.6 93.3 93.3 93.3
Percent
Protein Identity: 32.4 N.A. N.A. 35.2 32.8 38
Protein Similarity: 45.5 N.A. N.A. 47.9 50.3 54.4
P-Site Identity: 53.3 N.A. N.A. 53.3 40 40
P-Site Similarity: 73.3 N.A. N.A. 73.3 66.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 0 13 0 0 0 0 0 94 0 % C
% Asp: 0 19 0 7 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 57 0 69 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 13 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 25 0 0 0 0 0 0 % I
% Lys: 75 0 0 0 0 0 88 0 0 69 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 7 0 0 75 0 0 0 0 0 94 % L
% Met: 0 0 0 0 0 7 0 0 0 19 0 0 13 0 0 % M
% Asn: 0 7 0 7 0 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 100 13 0 0 0 0 0 0 0 100 0 7 0 % P
% Gln: 13 0 0 7 0 0 7 0 0 0 0 0 57 0 0 % Q
% Arg: 0 19 0 0 0 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % T
% Val: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 100 0 0 69 0 0 88 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _