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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL1
All Species:
23.64
Human Site:
Y78
Identified Species:
43.33
UniProt:
Q9Y3C6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C6
NP_057143.1
166
18237
Y78
G
R
G
G
A
S
I
Y
G
K
Q
F
E
D
E
Chimpanzee
Pan troglodytes
XP_001173312
147
16120
D65
I
Y
G
K
Q
F
E
D
E
L
H
P
D
L
K
Rhesus Macaque
Macaca mulatta
XP_001096296
130
14390
Y48
E
V
A
R
R
G
Y
Y
N
G
T
K
F
R
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0W5
166
18218
Y78
G
R
G
G
A
S
I
Y
G
K
Q
F
E
D
E
Rat
Rattus norvegicus
Q812D3
161
18095
Y78
F
E
D
E
Y
S
E
Y
L
K
H
N
V
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509065
166
18073
Y78
G
R
G
G
A
S
I
Y
G
K
Q
F
E
D
E
Chicken
Gallus gallus
Q5ZLV2
161
18033
Y78
F
E
D
E
F
S
E
Y
L
K
H
S
V
R
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001029350
166
18212
Y78
G
R
G
G
A
S
I
Y
G
K
Q
F
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523874
176
19507
Y87
G
R
G
G
A
S
I
Y
G
S
E
F
A
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52014
201
21845
I100
D
G
T
G
G
R
S
I
Y
G
E
R
F
E
D
Sea Urchin
Strong. purpuratus
XP_780113
162
17781
F78
N
S
I
W
G
K
Q
F
E
D
E
I
T
T
D
Poplar Tree
Populus trichocarpa
XP_002322812
164
18042
Y76
G
R
G
G
K
S
I
Y
G
D
K
F
E
D
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SF72
163
17809
I77
G
E
K
F
E
D
E
I
H
P
G
L
K
H
T
Conservation
Percent
Protein Identity:
100
88.5
74.6
N.A.
N.A.
98.1
45.7
N.A.
95.1
45.7
N.A.
84.9
N.A.
69.8
N.A.
41.2
69.8
Protein Similarity:
100
88.5
75.9
N.A.
N.A.
100
64.4
N.A.
98.1
63.2
N.A.
92.1
N.A.
80.1
N.A.
58.7
81.9
P-Site Identity:
100
6.6
6.6
N.A.
N.A.
100
20
N.A.
100
20
N.A.
100
N.A.
80
N.A.
6.6
0
P-Site Similarity:
100
20
6.6
N.A.
N.A.
100
20
N.A.
100
20
N.A.
100
N.A.
86.6
N.A.
26.6
20
Percent
Protein Identity:
65
N.A.
N.A.
N.A.
N.A.
68
Protein Similarity:
81.9
N.A.
N.A.
N.A.
N.A.
79.5
P-Site Identity:
80
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
39
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
0
8
0
8
0
16
0
0
8
47
16
% D
% Glu:
8
24
0
16
8
0
31
0
16
0
24
0
39
8
47
% E
% Phe:
16
0
0
8
8
8
0
8
0
0
0
47
16
0
0
% F
% Gly:
54
8
54
54
16
8
0
0
47
16
8
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
8
0
24
0
0
8
0
% H
% Ile:
8
0
8
0
0
0
47
16
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
8
8
8
0
0
0
47
8
8
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
16
8
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
0
31
0
0
0
0
% Q
% Arg:
0
47
0
8
8
8
0
0
0
0
0
8
0
24
8
% R
% Ser:
0
8
0
0
0
62
8
0
0
8
0
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
8
0
8
8
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
8
70
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _