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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC53
All Species:
6.06
Human Site:
T181
Identified Species:
13.33
UniProt:
Q9Y3C0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C0
NP_057137.1
194
21173
T181
P
D
G
E
S
E
K
T
V
E
E
S
S
D
S
Chimpanzee
Pan troglodytes
XP_001156073
194
21180
T181
P
D
G
E
I
E
K
T
V
E
E
S
S
D
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532668
194
21291
N181
P
D
G
E
G
E
K
N
T
E
E
S
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR27
194
21074
A181
P
N
G
E
S
E
R
A
V
E
E
S
S
D
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507211
217
23907
M204
T
D
G
K
S
E
V
M
A
E
D
N
S
D
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DKA1
199
21666
E186
P
V
P
D
G
E
P
E
A
E
E
S
S
D
S
Zebra Danio
Brachydanio rerio
Q5RGJ6
200
21547
Q187
S
K
K
R
L
E
E
Q
D
D
D
S
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLT8
176
19483
D164
G
L
E
P
R
I
L
D
T
P
D
L
I
L
A
Honey Bee
Apis mellifera
XP_001121894
160
18632
K148
E
S
Q
Q
V
I
S
K
Q
I
S
T
E
N
D
Nematode Worm
Caenorhab. elegans
O01901
189
20934
N174
P
Q
A
Q
T
S
R
N
Y
E
S
S
G
E
S
Sea Urchin
Strong. purpuratus
XP_001203060
179
19389
S167
E
S
D
S
D
D
F
S
S
Q
D
N
S
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.2
N.A.
90.2
N.A.
N.A.
70.5
N.A.
73.8
63.5
N.A.
34.5
36.5
27.8
41.2
Protein Similarity:
100
99.4
N.A.
93.3
N.A.
95.8
N.A.
N.A.
76.9
N.A.
85.9
78.5
N.A.
54.1
56.7
48.9
61.8
P-Site Identity:
100
93.3
N.A.
80
N.A.
80
N.A.
N.A.
53.3
N.A.
53.3
26.6
N.A.
0
0
26.6
6.6
P-Site Similarity:
100
93.3
N.A.
80
N.A.
93.3
N.A.
N.A.
73.3
N.A.
60
46.6
N.A.
13.3
20
53.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
19
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
37
10
10
10
10
0
10
10
10
37
0
0
55
19
% D
% Glu:
19
0
10
37
0
64
10
10
0
64
46
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
46
0
19
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
19
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
10
10
10
0
0
28
10
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
10
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
19
0
0
0
19
0
10
0
% N
% Pro:
55
0
10
10
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
0
10
10
19
0
0
0
10
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
19
0
0
0
0
0
0
0
0
% R
% Ser:
10
19
0
10
28
10
10
10
10
0
19
64
73
10
73
% S
% Thr:
10
0
0
0
10
0
0
19
19
0
0
10
0
0
0
% T
% Val:
0
10
0
0
10
0
10
0
28
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _