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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3B14 All Species: 6.44
Human Site: T121 Identified Species: 17.71
UniProt: Q9Y3B4 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3B4 NP_057131.1 125 14585 T121 K E K Y G I N T D P P K _ _ _
Chimpanzee Pan troglodytes XP_001144087 110 12759
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079940 125 14564 T121 K E K Y G I N T D P P K _ _ _
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRV7 121 14176 T117 K A K Y N L K T P E A P _ _ _
Honey Bee Apis mellifera XP_394807 123 14462
Nematode Worm Caenorhab. elegans Q8ITY4 138 15988 G121 K E R Y G I G G D I D K E K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002313271 124 14438 G119 V K M Q E K Y G V T T K D _ _
Maize Zea mays NP_001148369 129 14464 K121 E K Y G I G S K T P G P G S T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FMP4 124 14364
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 97.5 N.A. N.A. 72 76.8 61.5 N.A.
Protein Similarity: 100 88 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 98.4 N.A. N.A. 84.8 87.1 76 N.A.
P-Site Identity: 100 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 100 N.A. N.A. 33.3 0 46.6 N.A.
P-Site Similarity: 100 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 100 N.A. N.A. 41.6 0 53.3 N.A.
Percent
Protein Identity: 63.2 63.5 N.A. 62.4 N.A. N.A.
Protein Similarity: 78.4 77.5 N.A. 79.2 N.A. N.A.
P-Site Identity: 7.6 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 15.3 33.3 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 34 0 12 0 12 0 0 % D
% Glu: 12 34 0 0 12 0 0 0 0 12 0 0 12 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 34 12 12 23 0 0 12 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 34 0 0 0 12 0 0 0 0 0 % I
% Lys: 45 23 34 0 0 12 12 12 0 0 0 45 0 12 0 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 23 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 12 34 23 23 0 0 0 % P
% Gln: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % S
% Thr: 0 0 0 0 0 0 0 34 12 12 12 0 0 0 12 % T
% Val: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 45 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 34 45 45 % _