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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC1
All Species:
9.09
Human Site:
T102
Identified Species:
25
UniProt:
Q9Y3B2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B2
NP_057130.1
195
21452
T102
L
K
N
S
F
R
G
T
I
R
K
E
D
V
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534981
195
21435
T102
L
K
N
S
F
R
G
T
I
R
K
E
D
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAA6
195
21405
T102
L
K
N
A
F
R
G
T
I
R
K
E
D
I
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505605
155
16980
I63
K
N
S
F
R
G
T
I
R
K
E
D
V
R
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139039
194
21552
I102
K
D
R
F
R
G
T
I
R
R
E
D
V
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609492
204
22693
L106
L
E
S
S
Y
R
G
L
L
R
K
E
D
V
R
Honey Bee
Apis mellifera
XP_624453
198
22179
I104
L
T
R
P
Y
R
G
I
L
R
K
E
D
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784560
162
18087
I69
T
E
T
F
R
G
M
I
R
K
E
D
I
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53859
292
31565
G113
I
L
V
S
V
L
P
G
T
E
K
G
R
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
96.9
N.A.
95.9
N.A.
N.A.
64
N.A.
N.A.
79.4
N.A.
46.5
48.4
N.A.
50.2
Protein Similarity:
100
N.A.
N.A.
98.4
N.A.
99.4
N.A.
N.A.
70.7
N.A.
N.A.
90.2
N.A.
65.6
66.1
N.A.
65.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
6.6
N.A.
66.6
60
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
26.6
N.A.
N.A.
20
N.A.
93.3
73.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
34
56
0
0
% D
% Glu:
0
23
0
0
0
0
0
0
0
12
34
56
0
0
0
% E
% Phe:
0
0
0
34
34
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
34
56
12
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
45
34
0
0
0
12
12
0
% I
% Lys:
23
34
0
0
0
0
0
0
0
23
67
0
0
12
0
% K
% Leu:
56
12
0
0
0
12
0
12
23
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
34
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
23
0
34
56
0
0
34
67
0
0
12
34
56
% R
% Ser:
0
0
23
45
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
12
12
12
0
0
0
23
34
12
0
0
0
0
0
12
% T
% Val:
0
0
12
0
12
0
0
0
0
0
0
0
23
45
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _