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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2J1 All Species: 26.97
Human Site: S192 Identified Species: 37.08
UniProt: Q9Y385 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y385 NP_057105.2 318 35199 S192 F K A E V N S S G K T I S E S
Chimpanzee Pan troglodytes XP_518636 318 35166 S192 F K A E V N S S G K T I S E S
Rhesus Macaque Macaca mulatta XP_001096217 318 35120 S192 F K A E V N S S G K T I S E S
Dog Lupus familis XP_532230 305 33567 T180 E V N S S G K T I A E P D L N
Cat Felis silvestris
Mouse Mus musculus Q9JJZ4 318 34971 S192 F K A E V N S S G K T I A E S
Rat Rattus norvegicus NP_001100112 249 27861 E124 G F M P T K G E G A I G S L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513572 437 47819 S312 F K A E V N S S G K S L T V P
Chicken Gallus gallus NP_990094 317 34755 S192 F K A E V H S S R K S E A E P
Frog Xenopus laevis NP_001091402 302 33372 L177 A D V E A R E L A R Q I S F K
Zebra Danio Brachydanio rerio NP_999932 314 34258 S189 N F K A E S S S S A A D S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393288 265 29807 Q140 D Y S K E E R Q K L A K K S L
Nematode Worm Caenorhab. elegans NP_001040755 314 35297 V189 L K F Q D E S V V K K E V E A
Sea Urchin Strong. purpuratus XP_792623 370 40402 S191 K E E K K P S S T S E S S P P
Poplar Tree Populus trichocarpa XP_002312335 310 34437 S185 Q Q N P A Q G S E E H P N N S
Maize Zea mays NP_001150768 309 33945 V184 I P Q T L P N V P N E E L A P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LSP7 309 34304 C184 P K P L P L E C S Q A P S I V
Baker's Yeast Sacchar. cerevisiae P33296 250 28365 S124 S D E A T T G S I T T S D H Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.8 89.9 N.A. 92.4 71.3 N.A. 61.5 76.7 73.2 66 N.A. N.A. 48.1 44.6 46.2
Protein Similarity: 100 100 98.1 91.1 N.A. 94.6 74.5 N.A. 64.9 82.6 80.8 76.7 N.A. N.A. 61.3 61.9 58.1
P-Site Identity: 100 100 100 0 N.A. 93.3 13.3 N.A. 66.6 60 20 26.6 N.A. N.A. 0 26.6 20
P-Site Similarity: 100 100 100 13.3 N.A. 100 13.3 N.A. 86.6 80 26.6 33.3 N.A. N.A. 13.3 40 33.3
Percent
Protein Identity: 38.9 34.9 N.A. 36.1 28.6 N.A.
Protein Similarity: 55.3 54 N.A. 54.4 45.9 N.A.
P-Site Identity: 13.3 0 N.A. 13.3 13.3 N.A.
P-Site Similarity: 33.3 13.3 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 36 12 12 0 0 0 6 18 18 0 12 6 6 % A
% Cys: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % C
% Asp: 6 12 0 0 6 0 0 0 0 0 0 6 12 0 6 % D
% Glu: 6 6 12 42 12 12 12 6 6 6 18 18 0 36 0 % E
% Phe: 36 12 6 0 0 0 0 0 0 0 0 0 0 6 0 % F
% Gly: 6 0 0 0 0 6 18 0 36 0 0 6 0 0 0 % G
% His: 0 0 0 0 0 6 0 0 0 0 6 0 0 6 0 % H
% Ile: 6 0 0 0 0 0 0 0 12 0 6 30 0 6 0 % I
% Lys: 6 48 6 12 6 6 6 0 6 42 6 6 6 0 6 % K
% Leu: 6 0 0 6 6 6 0 6 0 6 0 6 6 12 6 % L
% Met: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 12 0 0 30 6 0 0 6 0 0 6 6 6 % N
% Pro: 6 6 6 12 6 12 0 0 6 0 0 18 0 6 24 % P
% Gln: 6 6 6 6 0 6 0 6 0 6 6 0 0 0 6 % Q
% Arg: 0 0 0 0 0 6 6 0 6 6 0 0 0 0 0 % R
% Ser: 6 0 6 6 6 6 53 59 12 6 12 12 48 12 36 % S
% Thr: 0 0 0 6 12 6 0 6 6 6 30 0 6 0 0 % T
% Val: 0 6 6 0 36 0 0 12 6 0 0 0 6 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _