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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMX2
All Species:
9.7
Human Site:
T283
Identified Species:
17.78
UniProt:
Q9Y320
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y320
NP_001137484.1
296
34038
T283
E
E
Q
P
V
A
S
T
P
T
T
V
S
D
G
Chimpanzee
Pan troglodytes
XP_001144536
296
34069
T283
E
E
Q
P
V
A
S
T
P
T
T
V
S
D
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533172
296
34072
T283
E
E
Q
P
V
A
P
T
P
T
E
V
P
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D710
295
33924
P283
E
K
P
V
D
P
A
P
T
T
V
P
D
G
E
Rat
Rattus norvegicus
Q5XIK2
295
33847
P283
E
K
P
G
N
P
T
P
T
A
V
P
D
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519394
400
45495
A387
E
E
P
P
E
P
P
A
A
A
T
L
P
P
G
Chicken
Gallus gallus
XP_426410
296
33860
A283
E
E
P
P
E
G
Q
A
A
A
G
L
A
N
G
Frog
Xenopus laevis
Q58E26
287
33106
S274
I
R
K
H
Q
E
E
S
I
H
E
N
E
W
N
Zebra Danio
Brachydanio rerio
Q6IQC7
307
35704
S283
R
P
S
E
L
V
F
S
T
V
P
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JW12
271
31304
R259
L
Y
K
E
A
I
E
R
L
P
I
A
P
K
E
Honey Bee
Apis mellifera
XP_394865
268
31092
P256
Y
R
D
C
K
K
N
P
I
K
K
K
E
K
K
Nematode Worm
Caenorhab. elegans
Q18484
265
30882
E252
D
L
L
N
L
Y
N
E
Q
K
E
K
K
G
A
Sea Urchin
Strong. purpuratus
XP_790165
224
25476
K211
K
S
Q
K
K
A
D
K
Q
E
A
K
A
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
96.2
N.A.
92.5
93.2
N.A.
49.7
86.1
76
71
N.A.
40.2
35.1
34.7
32.7
Protein Similarity:
100
99.3
N.A.
96.9
N.A.
95.9
95.9
N.A.
54.2
92.2
88.8
84
N.A.
60.1
57.4
54
50.3
P-Site Identity:
100
100
N.A.
80
N.A.
13.3
6.6
N.A.
33.3
26.6
0
0
N.A.
0
0
0
13.3
P-Site Similarity:
100
100
N.A.
80
N.A.
26.6
20
N.A.
40
46.6
13.3
20
N.A.
6.6
6.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
31
8
16
16
24
8
8
16
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
8
0
0
0
0
0
16
24
0
% D
% Glu:
54
39
0
16
16
8
16
8
0
8
24
8
24
8
39
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
8
0
0
24
39
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
16
0
8
0
0
0
0
% I
% Lys:
8
16
16
8
16
8
0
8
0
16
8
24
8
16
8
% K
% Leu:
8
8
8
0
16
0
0
0
8
0
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
16
0
0
0
0
8
0
8
8
% N
% Pro:
0
8
31
39
0
24
16
24
24
8
8
16
24
8
0
% P
% Gln:
0
0
31
0
8
0
8
0
16
0
0
0
0
8
0
% Q
% Arg:
8
16
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
16
16
0
0
0
0
16
0
0
% S
% Thr:
0
0
0
0
0
0
8
24
24
31
24
0
0
0
0
% T
% Val:
0
0
0
8
24
8
0
0
0
8
16
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _