KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMX2
All Species:
30
Human Site:
T210
Identified Species:
55
UniProt:
Q9Y320
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y320
NP_001137484.1
296
34038
T210
S
T
R
Y
K
V
S
T
S
P
L
T
K
Q
L
Chimpanzee
Pan troglodytes
XP_001144536
296
34069
T210
S
T
R
Y
K
V
S
T
S
P
L
T
K
Q
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533172
296
34072
T210
S
V
R
Y
K
V
S
T
S
P
L
T
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D710
295
33924
T210
S
T
R
Y
K
V
S
T
S
P
L
T
R
Q
L
Rat
Rattus norvegicus
Q5XIK2
295
33847
T210
S
T
R
Y
K
V
S
T
S
P
L
T
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519394
400
45495
R311
S
T
R
R
P
L
R
R
D
E
R
R
M
A
R
Chicken
Gallus gallus
XP_426410
296
33860
T210
S
T
R
Y
K
V
S
T
S
P
L
T
K
Q
L
Frog
Xenopus laevis
Q58E26
287
33106
P210
S
C
R
Y
S
I
S
P
S
P
L
S
K
Q
L
Zebra Danio
Brachydanio rerio
Q6IQC7
307
35704
T210
S
K
K
Y
R
V
S
T
S
P
L
S
K
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JW12
271
31304
A195
I
G
R
F
P
D
V
A
Q
K
Y
R
I
S
D
Honey Bee
Apis mellifera
XP_394865
268
31092
L192
G
R
Y
P
D
A
A
L
K
Y
H
I
S
D
A
Nematode Worm
Caenorhab. elegans
Q18484
265
30882
W188
G
K
L
D
I
G
R
W
A
K
E
G
E
R
F
Sea Urchin
Strong. purpuratus
XP_790165
224
25476
S147
A
E
I
F
Q
V
D
S
S
S
L
T
K
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
96.2
N.A.
92.5
93.2
N.A.
49.7
86.1
76
71
N.A.
40.2
35.1
34.7
32.7
Protein Similarity:
100
99.3
N.A.
96.9
N.A.
95.9
95.9
N.A.
54.2
92.2
88.8
84
N.A.
60.1
57.4
54
50.3
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
100
N.A.
20
100
66.6
73.3
N.A.
6.6
0
0
46.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
26.6
100
80
93.3
N.A.
13.3
6.6
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
8
8
0
0
0
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
8
8
0
8
0
0
0
0
8
8
% D
% Glu:
0
8
0
0
0
0
0
0
0
8
8
0
8
0
0
% E
% Phe:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
16
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
8
0
8
8
0
0
0
0
0
8
8
0
0
% I
% Lys:
0
16
8
0
47
0
0
0
8
16
0
0
62
0
0
% K
% Leu:
0
0
8
0
0
8
0
8
0
0
70
0
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
16
0
0
8
0
62
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
70
0
% Q
% Arg:
0
8
70
8
8
0
16
8
0
0
8
16
8
8
8
% R
% Ser:
70
0
0
0
8
0
62
8
70
8
0
16
8
8
0
% S
% Thr:
0
47
0
0
0
0
0
54
0
0
0
54
0
0
0
% T
% Val:
0
8
0
0
0
62
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
62
0
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _