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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMX2
All Species:
37.27
Human Site:
T145
Identified Species:
68.33
UniProt:
Q9Y320
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y320
NP_001137484.1
296
34038
T145
I
K
Y
F
N
D
K
T
I
D
E
E
L
E
R
Chimpanzee
Pan troglodytes
XP_001144536
296
34069
T145
I
K
Y
F
N
D
K
T
I
D
E
E
L
E
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533172
296
34072
T145
I
K
Y
F
N
D
K
T
I
D
E
E
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D710
295
33924
T145
I
K
Y
F
N
D
K
T
I
D
E
E
L
E
R
Rat
Rattus norvegicus
Q5XIK2
295
33847
T145
I
K
Y
F
N
D
K
T
I
D
E
E
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519394
400
45495
T246
I
K
Y
F
N
D
K
T
I
D
E
E
L
E
R
Chicken
Gallus gallus
XP_426410
296
33860
T145
I
K
Y
F
S
D
K
T
I
D
E
E
L
E
R
Frog
Xenopus laevis
Q58E26
287
33106
T145
I
K
Y
F
S
D
K
T
L
E
E
E
M
Q
S
Zebra Danio
Brachydanio rerio
Q6IQC7
307
35704
T145
I
K
Y
F
S
D
K
T
I
D
E
E
L
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JW12
271
31304
T130
Y
R
G
P
E
H
I
T
Y
F
R
N
A
Q
V
Honey Bee
Apis mellifera
XP_394865
268
31092
Y127
Q
G
P
E
K
V
T
Y
L
R
G
A
N
G
L
Nematode Worm
Caenorhab. elegans
Q18484
265
30882
G123
F
P
E
P
V
Y
N
G
P
E
Q
V
T
Y
F
Sea Urchin
Strong. purpuratus
XP_790165
224
25476
A82
I
V
Y
F
K
G
D
A
L
E
D
E
L
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
96.2
N.A.
92.5
93.2
N.A.
49.7
86.1
76
71
N.A.
40.2
35.1
34.7
32.7
Protein Similarity:
100
99.3
N.A.
96.9
N.A.
95.9
95.9
N.A.
54.2
92.2
88.8
84
N.A.
60.1
57.4
54
50.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
93.3
60
86.6
N.A.
6.6
0
0
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
20
6.6
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
70
8
0
0
62
8
0
0
0
0
% D
% Glu:
0
0
8
8
8
0
0
0
0
24
70
77
0
62
0
% E
% Phe:
8
0
0
77
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
8
8
0
0
8
0
8
0
0
8
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
77
0
0
0
0
0
8
0
62
0
0
0
0
0
0
% I
% Lys:
0
70
0
0
16
0
70
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
24
0
0
0
70
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
47
0
8
0
0
0
0
8
8
0
8
% N
% Pro:
0
8
8
16
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
54
% R
% Ser:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
8
77
0
0
0
0
8
0
0
% T
% Val:
0
8
0
0
8
8
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
77
0
0
8
0
8
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _