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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTO1
All Species:
8.79
Human Site:
T643
Identified Species:
17.58
UniProt:
Q9Y2Z2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Z2
NP_001116698.1
717
79964
T643
P
K
D
L
D
Y
L
T
I
R
D
V
S
L
S
Chimpanzee
Pan troglodytes
XP_527435
717
79827
T643
P
K
D
L
D
Y
L
T
I
R
D
V
S
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532202
672
74586
K600
F
H
Q
Q
Q
Q
I
K
E
V
Q
Q
D
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q923Z3
669
74313
E600
Y
Q
L
Q
E
I
K
E
V
Q
Q
D
E
A
L
Rat
Rattus norvegicus
NP_001100311
679
75393
L609
Q
Q
D
E
A
L
Q
L
P
Q
D
L
D
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506626
1086
120246
S943
P
E
D
L
D
Y
M
S
I
Q
T
V
S
L
S
Chicken
Gallus gallus
NP_001073232
646
71985
I577
N
S
S
R
P
Q
T
I
G
A
V
S
R
I
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611677
661
73577
V592
V
D
E
Q
Q
R
D
V
E
D
V
R
R
E
E
Honey Bee
Apis mellifera
XP_394417
770
86576
A688
L
E
R
I
K
I
E
A
I
Y
A
P
S
I
K
Nematode Worm
Caenorhab. elegans
Q20680
638
71662
E569
R
M
K
A
K
K
Q
E
I
D
R
E
S
A
T
Sea Urchin
Strong. purpuratus
XP_783517
1272
137085
D660
L
E
L
P
E
D
L
D
Y
T
S
L
K
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53070
669
74197
F600
Y
I
V
K
Q
N
Q
F
V
K
A
F
Q
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
84.8
N.A.
82
82.5
N.A.
44.1
62.7
N.A.
N.A.
N.A.
51.4
47.2
46.2
26.9
Protein Similarity:
100
99.7
N.A.
88.4
N.A.
87.3
88.5
N.A.
54.1
74
N.A.
N.A.
N.A.
68.1
63.3
62.2
38.8
P-Site Identity:
100
100
N.A.
0
N.A.
0
13.3
N.A.
66.6
0
N.A.
N.A.
N.A.
0
13.3
13.3
20
P-Site Similarity:
100
100
N.A.
13.3
N.A.
26.6
33.3
N.A.
93.3
6.6
N.A.
N.A.
N.A.
6.6
33.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
61.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
9
0
9
17
0
0
25
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
34
0
25
9
9
9
0
17
25
9
17
0
9
% D
% Glu:
0
25
9
9
17
0
9
17
17
0
0
9
9
17
9
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
17
9
9
42
0
0
0
0
17
0
% I
% Lys:
0
17
9
9
17
9
9
9
0
9
0
0
9
0
9
% K
% Leu:
17
0
17
25
0
9
25
9
0
0
0
17
0
34
17
% L
% Met:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
25
0
0
9
9
0
0
0
9
0
0
9
0
0
9
% P
% Gln:
9
17
9
25
25
17
25
0
0
25
17
9
9
0
0
% Q
% Arg:
9
0
9
9
0
9
0
0
0
17
9
9
17
0
0
% R
% Ser:
0
9
9
0
0
0
0
9
0
0
9
9
42
0
34
% S
% Thr:
0
0
0
0
0
0
9
17
0
9
9
0
0
0
9
% T
% Val:
9
0
9
0
0
0
0
9
17
9
17
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
25
0
0
9
9
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _