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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP58
All Species:
47.27
Human Site:
Y419
Identified Species:
65
UniProt:
Q9Y2X3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2X3
NP_057018.1
529
59578
Y419
A
L
A
K
T
E
K
Y
E
H
K
S
E
V
K
Chimpanzee
Pan troglodytes
XP_516036
529
59534
Y419
A
L
A
K
T
E
K
Y
E
H
K
S
E
V
K
Rhesus Macaque
Macaca mulatta
XP_001101291
530
59647
Y419
A
L
A
K
T
E
K
Y
E
H
K
S
E
V
K
Dog
Lupus familis
XP_849592
535
60159
Y419
A
L
A
K
T
E
K
Y
E
H
K
S
E
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW4
536
60324
Y419
A
L
A
K
A
E
K
Y
E
H
K
S
E
V
K
Rat
Rattus norvegicus
Q9QZ86
534
60052
Y419
A
L
A
K
A
E
K
Y
E
H
K
S
E
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517321
488
54610
Y379
A
L
A
K
A
D
K
Y
L
N
R
S
E
V
K
Chicken
Gallus gallus
XP_421942
527
59248
Y420
A
L
A
R
A
D
K
Y
Q
N
K
S
E
I
K
Frog
Xenopus laevis
NP_001086628
534
59844
Y420
A
L
A
R
A
E
K
Y
Q
H
K
S
E
V
R
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
R417
L
G
K
S
G
S
G
R
V
R
Q
A
Q
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477412
511
57152
Y420
A
K
A
K
F
E
K
Y
Q
A
K
S
E
V
F
Honey Bee
Apis mellifera
XP_395309
541
60693
Y419
A
K
A
K
F
E
K
Y
H
T
K
S
E
Y
M
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
C390
S
I
A
A
R
V
D
C
F
S
E
T
P
V
S
Sea Urchin
Strong. purpuratus
XP_781458
535
59905
Y420
S
K
A
K
F
E
K
Y
Q
H
K
S
E
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
Y418
G
K
P
K
I
E
V
Y
N
K
D
K
K
M
G
Baker's Yeast
Sacchar. cerevisiae
Q12499
511
56938
T422
E
A
K
K
V
E
M
T
E
A
R
A
Y
N
A
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
L459
A
E
A
P
K
K
P
L
I
Q
E
V
E
M
Q
Conservation
Percent
Protein Identity:
100
99.4
99.4
97
N.A.
94.7
95.1
N.A.
73.3
79.2
76
22.1
N.A.
61.2
60.8
38
66.7
Protein Similarity:
100
100
99.8
97.9
N.A.
96.6
96.4
N.A.
81.6
89.5
88
45.9
N.A.
75.6
75.5
56.1
81.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
66.6
60
73.3
6.6
N.A.
66.6
60
13.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
93.3
93.3
26.6
N.A.
73.3
60
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
48
46.5
Protein Similarity:
N.A.
N.A.
N.A.
72
67.1
62.1
P-Site Identity:
N.A.
N.A.
N.A.
20
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
71
6
83
6
30
0
0
0
0
12
0
12
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
6
0
0
0
6
0
0
0
0
% D
% Glu:
6
6
0
0
0
71
0
0
42
0
12
0
77
0
0
% E
% Phe:
0
0
0
0
18
0
0
0
6
0
0
0
0
0
6
% F
% Gly:
6
6
0
0
6
0
6
0
0
0
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
0
6
48
0
0
0
0
0
% H
% Ile:
0
6
0
0
6
0
0
0
6
0
0
0
0
6
0
% I
% Lys:
0
24
12
71
6
6
71
0
0
6
65
6
6
0
48
% K
% Leu:
6
53
0
0
0
0
0
6
6
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
0
12
6
% M
% Asn:
0
0
0
0
0
0
0
0
6
12
0
0
0
6
6
% N
% Pro:
0
0
6
6
0
0
6
0
0
0
0
0
6
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
24
6
6
0
6
0
6
% Q
% Arg:
0
0
0
12
6
0
0
6
0
6
12
0
0
0
6
% R
% Ser:
12
0
0
6
0
6
0
0
0
6
0
71
0
0
6
% S
% Thr:
0
0
0
0
24
0
0
6
0
6
0
6
0
0
0
% T
% Val:
0
0
0
0
6
6
6
0
6
0
0
6
0
71
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _