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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP58 All Species: 47.88
Human Site: T409 Identified Species: 65.83
UniProt: Q9Y2X3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2X3 NP_057018.1 529 59578 T409 G I R K I S G T G K A L A K T
Chimpanzee Pan troglodytes XP_516036 529 59534 T409 G I R K I S G T G K A L A K T
Rhesus Macaque Macaca mulatta XP_001101291 530 59647 T409 G I R K I S G T G K A L A K T
Dog Lupus familis XP_849592 535 60159 T409 G I R K I S G T G K A L A K T
Cat Felis silvestris
Mouse Mus musculus Q6DFW4 536 60324 T409 G I R K I S G T G K A L A K A
Rat Rattus norvegicus Q9QZ86 534 60052 T409 G I R K I S G T G K A L A K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517321 488 54610 T369 G L R R I S G T G K A L A K A
Chicken Gallus gallus XP_421942 527 59248 T410 G I R R I S G T G K A L A R A
Frog Xenopus laevis NP_001086628 534 59844 T410 G L K R I S G T G K A L A R A
Zebra Danio Brachydanio rerio Q7SXM7 508 56455 L407 Q E D L G F S L G Q L G K S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477412 511 57152 T410 N L R K L S G T G K A K A K F
Honey Bee Apis mellifera XP_395309 541 60693 T409 N L R R I S G T G K A K A K F
Nematode Worm Caenorhab. elegans Q21276 486 54493 N380 R V S R Y L A N K C S I A A R
Sea Urchin Strong. purpuratus XP_781458 535 59905 T410 D E R R I S G T G K S K A K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAB3 533 58985 S408 D L G R L S G S S K G K P K I
Baker's Yeast Sacchar. cerevisiae Q12499 511 56938 V412 D L R T T P K V V R E A K K V
Red Bread Mold Neurospora crassa Q8X066 597 66063 A449 N I D A D G L A A D A E A P K
Conservation
Percent
Protein Identity: 100 99.4 99.4 97 N.A. 94.7 95.1 N.A. 73.3 79.2 76 22.1 N.A. 61.2 60.8 38 66.7
Protein Similarity: 100 100 99.8 97.9 N.A. 96.6 96.4 N.A. 81.6 89.5 88 45.9 N.A. 75.6 75.5 56.1 81.6
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 80 80 66.6 6.6 N.A. 66.6 66.6 6.6 60
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 13.3 N.A. 80 80 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 54.7 48 46.5
Protein Similarity: N.A. N.A. N.A. 72 67.1 62.1
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 20
P-Site Similarity: N.A. N.A. N.A. 53.3 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 6 0 0 6 6 6 0 71 6 83 6 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 18 0 12 0 6 0 0 0 0 6 0 0 0 0 0 % D
% Glu: 0 12 0 0 0 0 0 0 0 0 6 6 0 0 0 % E
% Phe: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 18 % F
% Gly: 53 0 6 0 6 6 77 0 77 0 6 6 0 0 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 48 0 0 65 0 0 0 0 0 0 6 0 0 6 % I
% Lys: 0 0 6 42 0 0 6 0 6 77 0 24 12 71 6 % K
% Leu: 0 36 0 6 12 6 6 6 0 0 6 53 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 18 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 6 0 0 0 0 0 0 6 6 0 % P
% Gln: 6 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Q
% Arg: 6 0 71 42 0 0 0 0 0 6 0 0 0 12 6 % R
% Ser: 0 0 6 0 0 77 6 6 6 0 12 0 0 6 0 % S
% Thr: 0 0 0 6 6 0 0 71 0 0 0 0 0 0 24 % T
% Val: 0 6 0 0 0 0 0 6 6 0 0 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _