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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TDRKH
All Species:
4.24
Human Site:
S519
Identified Species:
9.33
UniProt:
Q9Y2W6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2W6
NP_001077434.1
606
67025
S519
M
A
T
E
T
D
A
S
L
S
T
L
L
T
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108076
573
62636
L483
S
T
W
P
K
I
Y
L
Y
D
T
S
N
G
K
Dog
Lupus familis
XP_851426
551
60647
I465
S
S
Y
V
Q
T
G
I
S
T
W
P
K
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL1
560
62116
T474
P
K
I
Y
L
Y
D
T
S
D
E
K
K
L
D
Rat
Rattus norvegicus
XP_227438
560
61993
T474
P
K
V
Y
L
Y
D
T
S
N
G
K
K
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514669
319
34334
E233
Q
N
L
D
I
G
L
E
L
V
R
R
G
Y
A
Chicken
Gallus gallus
XP_423400
665
71440
F523
V
A
S
Q
L
G
M
F
S
P
I
A
L
Q
F
Frog
Xenopus laevis
NP_001089292
718
79433
S594
T
I
G
D
S
E
G
S
L
E
S
G
I
T
E
Zebra Danio
Brachydanio rerio
NP_001014377
573
63662
E483
L
Y
S
Y
S
H
S
E
I
S
S
W
P
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608657
576
63805
N490
R
S
S
T
P
S
S
N
S
D
S
T
I
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785759
489
55090
W403
Q
L
T
H
V
A
K
W
K
P
L
Q
A
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
85.3
82.6
N.A.
84.8
85.8
N.A.
29.8
39
36.3
38.2
N.A.
23.9
N.A.
N.A.
33.1
Protein Similarity:
100
N.A.
87.1
85.9
N.A.
88.1
88.6
N.A.
39.1
53.3
54.8
57.4
N.A.
42.5
N.A.
N.A.
49.6
P-Site Identity:
100
N.A.
6.6
0
N.A.
0
0
N.A.
6.6
13.3
26.6
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
13.3
13.3
N.A.
13.3
20
N.A.
13.3
33.3
60
53.3
N.A.
46.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
10
10
0
0
0
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
10
19
0
0
28
0
0
0
0
19
% D
% Glu:
0
0
0
10
0
10
0
19
0
10
10
0
0
10
28
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
19
19
0
0
0
10
10
10
10
0
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
10
10
0
10
10
0
10
0
19
10
10
% I
% Lys:
0
19
0
0
10
0
10
0
10
0
0
19
28
10
10
% K
% Leu:
10
10
10
0
28
0
10
10
28
0
10
10
19
19
0
% L
% Met:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
10
0
0
10
0
0
% N
% Pro:
19
0
0
10
10
0
0
0
0
19
0
10
10
0
0
% P
% Gln:
19
0
0
10
10
0
0
0
0
0
0
10
0
10
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
19
19
28
0
19
10
19
19
46
19
28
10
0
10
0
% S
% Thr:
10
10
19
10
10
10
0
19
0
10
19
10
0
19
0
% T
% Val:
10
0
10
10
10
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
10
0
0
10
10
0
0
0
% W
% Tyr:
0
10
10
28
0
19
10
0
10
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _