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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R2C
All Species:
27.58
Human Site:
S381
Identified Species:
55.15
UniProt:
Q9Y2T4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2T4
NP_065149.2
447
51515
S381
T
L
E
A
S
R
E
S
S
K
P
R
A
V
L
Chimpanzee
Pan troglodytes
XP_001156254
566
63958
S500
T
L
E
A
S
R
E
S
S
K
P
R
A
V
L
Rhesus Macaque
Macaca mulatta
XP_001091436
453
51968
S391
T
L
E
A
S
R
E
S
S
K
P
R
A
S
L
Dog
Lupus familis
XP_852811
561
64414
S495
T
L
E
A
S
R
E
S
S
K
P
R
A
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG02
447
51443
S381
T
L
E
A
S
R
E
S
S
K
P
R
A
V
L
Rat
Rattus norvegicus
P97888
447
51455
S381
T
L
E
A
S
R
E
S
S
K
P
R
A
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIY5
451
51997
S389
T
L
E
A
S
R
E
S
S
K
P
R
A
I
L
Frog
Xenopus laevis
A1L3L9
468
54505
N406
T
L
E
A
S
R
E
N
S
K
P
R
A
I
L
Zebra Danio
Brachydanio rerio
NP_001025293
443
51566
N381
T
L
E
A
S
R
E
N
S
K
P
R
A
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36872
499
56948
I438
T
L
E
A
S
R
D
I
I
K
P
K
T
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39247
501
56256
K430
A
A
T
L
E
A
S
K
N
P
M
R
R
Q
I
Baker's Yeast
Sacchar. cerevisiae
Q00362
526
59644
T392
N
D
N
G
I
V
K
T
F
D
E
H
N
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.8
79.9
77.5
N.A.
99.3
99.5
N.A.
N.A.
80.4
80.3
84.7
N.A.
66.5
N.A.
N.A.
N.A.
Protein Similarity:
100
77.7
90.5
79.1
N.A.
99.7
100
N.A.
N.A.
90.6
89.5
94.6
N.A.
78.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.5
43.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
61.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
84
0
9
0
0
0
0
0
0
75
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
84
0
9
0
75
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
9
9
0
0
0
0
25
9
% I
% Lys:
0
0
0
0
0
0
9
9
0
84
0
9
0
0
0
% K
% Leu:
0
84
0
9
0
0
0
0
0
0
0
0
0
0
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
17
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
84
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
84
0
0
0
0
0
84
9
0
0
% R
% Ser:
0
0
0
0
84
0
9
59
75
0
0
0
0
9
0
% S
% Thr:
84
0
9
0
0
0
0
9
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _