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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M1
All Species:
40.91
Human Site:
Y395
Identified Species:
64.29
UniProt:
Q9Y2T2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2T2
NP_036227.1
418
46939
Y395
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
L395
F
S
C
L
L
L
F
L
F
W
N
H
W
A
F
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
Y395
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Dog
Lupus familis
XP_546170
477
52895
Y454
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKC8
418
46918
Y395
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Rat
Rattus norvegicus
P53676
418
46963
Y395
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506462
418
46967
Y395
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Chicken
Gallus gallus
Q5ZMP7
418
46954
Y395
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Frog
Xenopus laevis
Q801Q8
435
49666
K410
Y
L
K
V
F
E
P
K
L
N
Y
S
D
H
D
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
K411
Y
L
K
V
F
E
S
K
L
N
Y
S
D
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
Y392
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Honey Bee
Apis mellifera
XP_624899
417
47249
Y394
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Nematode Worm
Caenorhab. elegans
P35602
422
48210
K399
R
Y
L
K
I
I
E
K
S
G
Y
Q
A
L
P
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
Y393
K
V
N
R
L
D
M
Y
G
E
K
Y
K
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
G439
I
P
Y
F
T
T
S
G
I
Q
V
R
Y
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99.7
87.6
N.A.
99.5
98.8
N.A.
97.3
95.4
25.7
25.4
N.A.
69.1
71.5
26
74.8
Protein Similarity:
100
90.8
99.7
87.6
N.A.
99.7
99.5
N.A.
99.5
97.8
49.4
49
N.A.
85.1
86.1
51.9
89.7
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
0
0
N.A.
100
100
0
100
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
13.3
13.3
N.A.
100
100
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
67
0
0
0
0
0
0
14
0
14
% D
% Glu:
0
0
0
0
0
14
7
0
0
67
0
0
0
0
0
% E
% Phe:
7
0
0
7
14
0
7
0
7
0
0
0
0
0
74
% F
% Gly:
0
0
0
0
0
0
0
7
67
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
14
0
% H
% Ile:
7
0
0
0
7
7
0
0
7
0
0
0
0
0
0
% I
% Lys:
67
0
14
7
0
0
0
20
0
0
67
0
67
0
7
% K
% Leu:
0
14
7
7
74
7
0
7
14
0
0
0
0
14
0
% L
% Met:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
67
0
0
0
0
0
0
14
7
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
7
0
0
0
0
0
0
67
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% Q
% Arg:
7
0
0
67
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
7
0
0
0
0
14
0
7
0
0
14
0
0
0
% S
% Thr:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
67
0
14
0
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% W
% Tyr:
14
7
7
0
0
0
0
67
0
0
20
67
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _