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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYL1
All Species:
36.97
Human Site:
S67
Identified Species:
67.78
UniProt:
Q9Y2S2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2S2
NP_057058.2
319
35419
S67
G
S
L
K
G
S
L
S
V
E
E
Q
L
S
L
Chimpanzee
Pan troglodytes
XP_001147059
297
33340
N58
S
L
I
S
G
C
P
N
I
Q
E
A
V
E
G
Rhesus Macaque
Macaca mulatta
XP_001086858
319
35329
S67
G
A
L
K
G
S
L
S
A
E
E
Q
L
S
L
Dog
Lupus familis
XP_543175
319
35414
S67
G
S
L
R
G
S
L
S
S
E
E
Q
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP3
319
35190
S67
G
S
L
K
G
S
L
S
A
E
R
Q
L
S
L
Rat
Rattus norvegicus
Q811X6
319
35323
G67
G
S
L
K
G
S
L
G
A
E
Q
Q
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518865
362
39761
S110
G
M
L
K
G
S
L
S
A
Q
K
Q
L
S
L
Chicken
Gallus gallus
NP_001026001
281
31242
S64
G
F
L
K
G
T
L
S
A
E
K
Q
L
A
L
Frog
Xenopus laevis
NP_001091202
319
35836
S67
E
M
L
R
G
S
L
S
L
E
D
Q
M
A
L
Zebra Danio
Brachydanio rerio
NP_001038806
315
35077
S67
K
M
L
R
G
N
L
S
A
A
E
Q
L
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573114
315
34768
T66
G
L
L
R
G
K
L
T
A
A
Q
Q
F
A
C
Honey Bee
Apis mellifera
NP_001129207
317
35842
T66
G
L
L
R
G
S
L
T
A
E
Q
Q
F
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794386
316
34985
S64
G
M
L
R
G
T
L
S
V
E
A
Q
F
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
98.1
82.7
N.A.
84
84.6
N.A.
65.4
58.6
61.7
55.1
N.A.
51
51.4
N.A.
51.4
Protein Similarity:
100
93
99.6
91.8
N.A.
93.7
93
N.A.
79
73.9
81.5
75.8
N.A.
70.2
70.5
N.A.
72.4
P-Site Identity:
100
13.3
86.6
86.6
N.A.
86.6
80
N.A.
73.3
66.6
53.3
53.3
N.A.
33.3
53.3
N.A.
60
P-Site Similarity:
100
46.6
93.3
93.3
N.A.
86.6
86.6
N.A.
86.6
86.6
86.6
66.6
N.A.
60
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
62
16
8
8
0
31
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
70
39
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
24
0
0
% F
% Gly:
77
0
0
0
100
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
0
47
0
8
0
0
0
0
16
0
0
8
0
% K
% Leu:
0
24
93
0
0
0
93
0
8
0
0
0
62
0
77
% L
% Met:
0
31
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
24
93
0
0
0
% Q
% Arg:
0
0
0
47
0
0
0
0
0
0
8
0
0
0
8
% R
% Ser:
8
31
0
8
0
62
0
70
8
0
0
0
0
54
0
% S
% Thr:
0
0
0
0
0
16
0
16
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
16
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _