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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRCH1
All Species:
11.52
Human Site:
S105
Identified Species:
28.15
UniProt:
Q9Y2L9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L9
NP_001157685.1
728
80885
S105
D
T
V
Q
A
D
L
S
K
N
R
L
V
E
V
Chimpanzee
Pan troglodytes
XP_001167119
767
85005
L94
A
D
L
S
R
N
R
L
S
E
I
P
I
E
A
Rhesus Macaque
Macaca mulatta
XP_001102903
768
84669
S122
D
T
T
Q
A
D
L
S
R
N
R
F
T
E
I
Dog
Lupus familis
XP_534123
767
85860
S175
W
P
G
K
P
D
L
S
K
N
R
L
V
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P62046
709
79014
S95
D
T
V
R
A
D
L
S
K
N
R
L
V
E
V
Rat
Rattus norvegicus
NP_001128199
677
75193
V94
D
L
S
K
N
R
L
V
E
V
P
M
E
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514226
691
77204
L94
V
S
L
E
T
L
N
L
Y
H
N
C
I
K
V
Chicken
Gallus gallus
Q5ZLN0
603
67457
N59
P
Q
H
V
W
R
I
N
L
D
T
P
E
E
A
Frog
Xenopus laevis
Q6GPJ5
605
67086
D61
S
V
W
R
I
N
V
D
T
P
P
E
A
H
Q
Zebra Danio
Brachydanio rerio
XP_689376
655
72257
L99
H
L
V
S
L
E
T
L
N
L
Y
H
N
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
45.1
74.1
N.A.
80
81
N.A.
79.6
20.8
20.8
56
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59
59.6
78.2
N.A.
84.6
85.1
N.A.
84.3
39.5
37.6
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
66.6
66.6
N.A.
93.3
13.3
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
80
73.3
N.A.
100
33.3
N.A.
46.6
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
30
0
0
0
0
0
0
0
10
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
10
% C
% Asp:
40
10
0
0
0
40
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
0
10
10
0
10
20
60
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
10
0
0
0
0
0
0
10
0
10
0
10
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
10
0
20
0
20
% I
% Lys:
0
0
0
20
0
0
0
0
30
0
0
0
0
10
0
% K
% Leu:
0
20
20
0
10
10
50
30
10
10
0
30
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
20
10
10
10
40
10
0
10
0
0
% N
% Pro:
10
10
0
0
10
0
0
0
0
10
20
20
0
0
0
% P
% Gln:
0
10
0
20
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
20
10
20
10
0
10
0
40
0
0
0
0
% R
% Ser:
10
10
10
20
0
0
0
40
10
0
0
0
0
0
0
% S
% Thr:
0
30
10
0
10
0
10
0
10
0
10
0
10
0
0
% T
% Val:
10
10
30
10
0
0
10
10
0
10
0
0
30
0
40
% V
% Trp:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _