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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4B
All Species:
23.33
Human Site:
S574
Identified Species:
57.04
UniProt:
Q9Y2L6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L6
NP_055938.1
980
111630
S574
R
I
H
F
R
K
S
S
I
N
E
Q
F
V
D
Chimpanzee
Pan troglodytes
XP_516575
1268
142846
S862
R
I
H
F
R
K
S
S
I
S
E
Q
F
V
D
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
S776
R
I
H
F
R
K
S
S
I
N
E
Q
F
V
D
Dog
Lupus familis
XP_541808
1260
142030
S854
R
I
H
F
R
K
S
S
V
N
E
Q
F
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q920B0
981
111548
S575
R
I
H
F
R
K
S
S
I
N
E
Q
F
M
D
Rat
Rattus norvegicus
P31977
586
69372
M182
W
H
A
E
H
R
G
M
L
K
D
S
A
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
S464
R
I
H
L
R
K
S
S
M
N
E
Q
F
L
E
Chicken
Gallus gallus
Q9PU45
583
68536
H179
I
Q
N
W
H
E
E
H
R
G
M
L
R
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
T231
T
K
L
W
L
G
V
T
S
V
G
L
N
I
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
V641
N
E
N
E
P
V
A
V
A
K
P
E
P
Q
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.7
81.6
73.8
N.A.
93.2
20.7
N.A.
75.5
21.4
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
33.4
Protein Similarity:
100
77.1
82.4
76
N.A.
96.4
36.6
N.A.
81.2
37
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
50.8
P-Site Identity:
100
93.3
100
93.3
N.A.
93.3
0
N.A.
73.3
6.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
93.3
26.6
N.A.
N.A.
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
60
% D
% Glu:
0
10
0
20
0
10
10
0
0
0
60
10
0
10
10
% E
% Phe:
0
0
0
50
0
0
0
0
0
0
0
0
60
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
10
10
0
0
0
0
% G
% His:
0
10
60
0
20
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
60
0
0
0
0
0
0
40
0
0
0
0
10
0
% I
% Lys:
0
10
0
0
0
60
0
0
0
20
0
0
0
0
0
% K
% Leu:
0
0
10
10
10
0
0
0
10
0
0
20
0
10
10
% L
% Met:
0
0
0
0
0
0
0
10
10
0
10
0
0
20
0
% M
% Asn:
10
0
20
0
0
0
0
0
0
50
0
0
10
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
60
0
10
0
% Q
% Arg:
60
0
0
0
60
10
0
0
10
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
60
60
10
10
0
10
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
10
10
10
10
0
0
0
40
0
% V
% Trp:
10
0
0
20
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _