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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4B
All Species:
23.64
Human Site:
S525
Identified Species:
57.78
UniProt:
Q9Y2L6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L6
NP_055938.1
980
111630
S525
E
D
I
I
P
S
E
S
S
S
L
S
D
T
T
Chimpanzee
Pan troglodytes
XP_516575
1268
142846
S813
E
D
I
I
P
S
E
S
S
S
L
S
D
T
T
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
S727
E
D
I
I
P
S
E
S
S
S
L
S
D
T
T
Dog
Lupus familis
XP_541808
1260
142030
S805
E
D
I
I
P
S
E
S
S
S
L
S
D
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q920B0
981
111548
S526
E
D
I
I
P
S
E
S
S
S
L
S
D
T
T
Rat
Rattus norvegicus
P31977
586
69372
K133
G
S
Y
A
V
Q
A
K
F
G
D
Y
N
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
S415
E
D
I
I
P
S
E
S
S
S
L
S
D
T
I
Chicken
Gallus gallus
Q9PU45
583
68536
V130
V
L
L
A
S
Y
A
V
Q
S
K
Y
G
D
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
I182
P
E
M
W
E
E
R
I
K
T
W
Y
M
D
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
S592
K
K
K
E
D
K
N
S
R
L
R
S
K
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.7
81.6
73.8
N.A.
93.2
20.7
N.A.
75.5
21.4
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
33.4
Protein Similarity:
100
77.1
82.4
76
N.A.
96.4
36.6
N.A.
81.2
37
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
50.8
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
6.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
13.3
N.A.
N.A.
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
20
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
0
0
10
0
0
0
0
0
10
0
60
20
0
% D
% Glu:
60
10
0
10
10
10
60
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
60
60
0
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
10
10
10
0
0
10
0
10
10
0
10
0
10
10
0
% K
% Leu:
0
10
10
0
0
0
0
0
0
10
60
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% R
% Ser:
0
10
0
0
10
60
0
70
60
70
0
70
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
60
50
% T
% Val:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
30
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _