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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4B
All Species:
22.42
Human Site:
S268
Identified Species:
54.81
UniProt:
Q9Y2L6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L6
NP_055938.1
980
111630
S268
D
P
R
R
I
S
V
S
R
R
T
F
G
Q
S
Chimpanzee
Pan troglodytes
XP_516575
1268
142846
S556
D
P
R
R
I
S
V
S
R
R
T
F
G
Q
S
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
S470
D
P
R
R
I
S
V
S
R
R
T
F
G
Q
S
Dog
Lupus familis
XP_541808
1260
142030
S547
D
P
R
R
I
S
V
S
R
R
T
F
G
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q920B0
981
111548
S268
D
P
R
R
I
S
V
S
R
R
T
F
G
Q
S
Rat
Rattus norvegicus
P31977
586
69372
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
R195
Q
H
Q
F
Y
L
D
R
K
Q
S
K
A
K
I
Chicken
Gallus gallus
Q9PU45
583
68536
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
S299
D
P
R
R
V
S
V
S
R
R
T
F
G
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.7
81.6
73.8
N.A.
93.2
20.7
N.A.
75.5
21.4
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
33.4
Protein Similarity:
100
77.1
82.4
76
N.A.
96.4
36.6
N.A.
81.2
37
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
50.8
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
0
N.A.
N.A.
N.A.
0
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
33.3
0
N.A.
N.A.
N.A.
0
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
60
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
10
0
10
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
10
0
0
0
50
0
% Q
% Arg:
0
0
60
60
0
0
0
10
60
60
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
60
0
60
0
0
10
0
0
0
60
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% T
% Val:
0
0
0
0
10
0
60
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _