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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK3
All Species:
15.76
Human Site:
S708
Identified Species:
34.67
UniProt:
Q9Y2K2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2K2
NP_079440.2
1263
139980
S708
P
H
G
A
A
S
S
S
Q
F
Q
G
L
P
S
Chimpanzee
Pan troglodytes
XP_508771
1263
139874
S708
P
H
G
A
A
S
S
S
Q
F
Q
G
L
P
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536563
1290
143819
S739
S
H
G
A
A
S
P
S
Q
F
P
G
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P4S6
1311
145765
S756
S
H
G
A
T
S
P
S
Q
F
Q
G
L
P
S
Rat
Rattus norvegicus
Q9R1U5
776
84890
L232
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517352
1230
134087
S662
S
H
G
A
A
P
S
S
Q
F
Q
G
L
P
S
Chicken
Gallus gallus
Q9IA88
798
88848
I254
S
E
D
C
E
T
L
I
R
R
M
L
V
V
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Y642
C
E
Q
L
Q
K
M
Y
A
A
P
Q
D
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
D829
A
Q
G
S
S
S
T
D
E
G
C
E
T
D
Q
Honey Bee
Apis mellifera
XP_395722
901
98876
D357
S
I
Q
S
I
P
G
D
Y
A
P
D
G
A
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798437
1066
118092
R522
K
Q
L
Q
T
T
V
R
T
S
Q
P
G
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
89
N.A.
88.4
28.5
N.A.
70.9
29.5
N.A.
58.4
N.A.
26.9
32.2
N.A.
30.7
Protein Similarity:
100
99.8
N.A.
92.1
N.A.
91.7
40.6
N.A.
76.8
43.5
N.A.
69.6
N.A.
38.6
44.9
N.A.
46
P-Site Identity:
100
100
N.A.
80
N.A.
80
6.6
N.A.
86.6
0
N.A.
0
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
80
N.A.
80
26.6
N.A.
86.6
20
N.A.
0
N.A.
40
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
46
37
0
0
0
10
19
0
0
0
10
0
% A
% Cys:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
19
0
0
0
10
10
19
10
% D
% Glu:
0
19
0
0
10
0
0
0
10
0
0
10
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% F
% Gly:
0
10
55
0
0
0
10
0
0
10
0
46
19
0
10
% G
% His:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
10
0
10
10
0
0
0
10
55
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
0
10
0
0
28
19
0
0
0
28
10
0
46
0
% P
% Gln:
0
19
19
10
10
0
0
0
46
10
46
10
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
19
10
10
0
0
0
10
% R
% Ser:
46
0
0
19
10
46
28
46
0
10
0
0
0
0
46
% S
% Thr:
0
0
0
0
19
19
19
0
10
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _