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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L3
All Species:
17.27
Human Site:
S435
Identified Species:
42.22
UniProt:
Q9Y2J2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2J2
NP_036439.2
1087
120678
S435
P
Y
F
E
R
S
S
S
K
R
Y
T
M
S
R
Chimpanzee
Pan troglodytes
XP_512036
1087
120712
S435
P
Y
F
E
R
S
S
S
K
R
Y
T
M
S
R
Rhesus Macaque
Macaca mulatta
XP_001104857
1245
138660
S537
P
H
F
E
R
T
S
S
K
R
V
S
R
S
L
Dog
Lupus familis
XP_537321
1116
123414
S437
P
Y
F
E
R
S
S
S
K
R
Y
T
M
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV92
929
103319
K312
G
V
D
L
H
H
A
K
D
S
E
G
V
E
I
Rat
Rattus norvegicus
Q9WTP0
879
98224
R262
M
E
L
H
K
T
Y
R
G
M
T
P
G
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512117
1058
117583
S401
P
Y
F
E
R
S
S
S
K
R
Y
T
M
S
R
Chicken
Gallus gallus
XP_419142
791
86601
A173
T
V
T
P
E
K
K
A
E
E
E
K
D
D
E
Frog
Xenopus laevis
P11434
801
89411
H184
E
G
E
S
K
A
S
H
K
V
V
R
R
S
P
Zebra Danio
Brachydanio rerio
O57457
619
70690
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
45.9
89.2
N.A.
71.7
44
N.A.
81.3
56.9
25.8
22.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
58.9
91.6
N.A.
77.4
56.4
N.A.
85.1
61.6
38.8
35.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
100
N.A.
0
0
N.A.
100
0
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
13.3
13.3
N.A.
100
13.3
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
10
0
0
0
10
10
0
% D
% Glu:
10
10
10
50
10
0
0
0
10
10
20
0
0
20
10
% E
% Phe:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
10
0
0
10
10
0
0
% G
% His:
0
10
0
10
10
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
20
10
10
10
60
0
0
10
0
0
0
% K
% Leu:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
40
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
10
0
0
0
0
0
0
0
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
50
0
0
10
0
50
0
10
20
0
40
% R
% Ser:
0
0
0
10
0
40
60
50
0
10
0
10
0
60
0
% S
% Thr:
10
0
10
0
0
20
0
0
0
0
10
40
0
0
0
% T
% Val:
0
20
0
0
0
0
0
0
0
10
20
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
40
0
0
0
0
10
0
0
0
40
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _