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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFR3B
All Species:
25.76
Human Site:
Y280
Identified Species:
62.96
UniProt:
Q9Y2G0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2G0
NP_055786.1
817
92487
Y280
R
C
F
K
I
I
M
Y
S
I
Q
P
Q
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532893
836
94596
Y299
R
C
F
K
I
I
M
Y
S
I
Q
P
Q
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ18
817
92388
Y280
R
C
F
K
I
I
M
Y
S
I
Q
P
Q
H
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508880
1075
119852
Y538
H
C
F
K
I
I
M
Y
S
I
Q
A
Q
Y
S
Chicken
Gallus gallus
XP_420019
845
95197
Y309
R
C
F
R
I
I
M
Y
S
I
Q
P
Q
H
S
Frog
Xenopus laevis
Q641A2
819
92526
Y282
S
C
F
K
I
I
M
Y
S
I
Q
A
Q
Y
S
Zebra Danio
Brachydanio rerio
Q5SPP5
816
91941
Y280
R
C
F
K
I
I
M
Y
S
I
Q
S
Q
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IGJ0
834
93943
I311
H
T
F
R
I
V
M
I
S
I
Q
P
Q
Y
S
Honey Bee
Apis mellifera
XP_001120727
795
89930
N259
P
V
L
R
H
L
D
N
H
Q
L
W
V
P
N
Nematode Worm
Caenorhab. elegans
Q09263
859
96649
R279
K
H
M
D
L
H
K
R
W
T
P
P
P
S
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
95.8
N.A.
97.5
N.A.
N.A.
47.6
86.3
62.5
80.6
N.A.
39.3
45.2
35.9
N.A.
Protein Similarity:
100
N.A.
N.A.
97
N.A.
98.9
N.A.
N.A.
59.5
92
77.4
90
N.A.
60.6
66.9
56.9
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
80
93.3
80
93.3
N.A.
60
0
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
86.6
100
86.6
93.3
N.A.
80
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% A
% Cys:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
20
10
0
0
10
10
0
0
10
0
0
0
0
50
0
% H
% Ile:
0
0
0
0
80
70
0
10
0
80
0
0
0
0
0
% I
% Lys:
10
0
0
60
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
10
10
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
80
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
10
60
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
80
0
80
0
0
% Q
% Arg:
50
0
0
30
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
80
0
0
10
0
10
80
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
10
0
0
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
30
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _