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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC17A4
All Species:
21.82
Human Site:
S452
Identified Species:
43.64
UniProt:
Q9Y2C5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2C5
NP_005486.1
497
54055
S452
T
A
A
G
F
F
I
S
Q
D
S
E
F
G
W
Chimpanzee
Pan troglodytes
XP_527248
497
54053
S452
T
A
A
G
F
F
I
S
Q
D
S
E
F
G
W
Rhesus Macaque
Macaca mulatta
XP_001082785
497
54256
S452
T
A
A
G
F
F
I
S
Q
D
S
E
F
G
W
Dog
Lupus familis
XP_545377
526
57357
S481
T
A
T
G
F
L
I
S
Q
D
S
V
S
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCM1
492
53649
S447
T
V
A
G
F
F
I
S
Q
D
S
E
F
G
W
Rat
Rattus norvegicus
Q62795
465
51332
D422
A
G
L
I
L
N
Q
D
P
E
Y
A
W
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519993
502
53998
S454
T
V
V
G
F
L
T
S
Q
D
A
L
T
G
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC8
576
63887
K461
L
I
V
G
A
M
T
K
H
K
T
R
E
E
W
Zebra Danio
Brachydanio rerio
Q1L8X9
590
64796
K474
L
I
V
G
A
L
T
K
H
K
T
R
L
E
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7S5
529
58354
S457
G
H
L
I
S
D
P
S
K
P
M
M
G
Q
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34644
576
63090
T463
P
F
V
T
E
A
F
T
A
H
S
K
H
G
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GX78
541
59595
V497
T
A
G
V
L
A
G
V
F
G
T
A
A
T
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.3
53.9
N.A.
78.2
44
N.A.
47.6
N.A.
26.9
27.4
N.A.
29.8
N.A.
24.8
N.A.
Protein Similarity:
100
99.8
98.9
69.9
N.A.
88.1
62.3
N.A.
62.7
N.A.
41.8
44.4
N.A.
50.8
N.A.
42.5
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
93.3
0
N.A.
53.3
N.A.
13.3
13.3
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
13.3
N.A.
60
N.A.
20
20
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
34
0
17
17
0
0
9
0
9
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
0
50
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
9
0
34
9
17
0
% E
% Phe:
0
9
0
0
50
34
9
0
9
0
0
0
34
0
0
% F
% Gly:
9
9
9
67
0
0
9
0
0
9
0
0
9
59
9
% G
% His:
0
9
0
0
0
0
0
0
17
9
0
0
9
9
0
% H
% Ile:
0
17
0
17
0
0
42
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
9
17
0
9
0
0
9
% K
% Leu:
17
0
17
0
17
25
0
0
0
0
0
9
9
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
9
0
9
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
50
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
59
0
0
50
0
9
0
0
% S
% Thr:
59
0
9
9
0
0
25
9
0
0
25
0
9
9
0
% T
% Val:
0
17
34
9
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
84
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _