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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE
All Species:
19.09
Human Site:
Y478
Identified Species:
42
UniProt:
Q9Y251
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y251
NP_001092010.1
543
61177
Y478
S
N
K
Q
V
D
K
Y
L
L
R
P
L
G
P
Chimpanzee
Pan troglodytes
XP_517183
543
61209
Y478
F
N
K
Q
V
D
K
Y
L
L
R
P
L
G
P
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
Y480
F
D
K
Q
V
D
K
Y
L
L
R
P
L
G
P
Dog
Lupus familis
XP_850908
545
61071
Y480
F
D
K
Q
V
D
K
Y
L
L
Q
P
L
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
Y470
F
R
K
P
V
D
T
Y
L
L
K
P
S
G
P
Rat
Rattus norvegicus
Q71RP1
536
60461
Y471
F
S
R
P
V
D
K
Y
L
L
K
P
F
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
G464
Q
Y
L
L
L
P
H
G
K
D
S
I
L
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038470
546
60923
L481
G
S
I
E
A
F
V
L
Q
S
D
E
A
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121450
528
60132
L464
H
K
N
S
K
V
F
L
Y
A
L
T
S
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
G418
E
Y
L
F
L
P
K
G
T
K
G
I
L
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
H480
Y
L
N
R
E
E
Y
H
L
T
P
E
N
G
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95
82.7
N.A.
76.8
75.8
N.A.
N.A.
60.2
N.A.
50.9
N.A.
N.A.
30.3
N.A.
30.3
Protein Similarity:
100
99.2
97.2
89.5
N.A.
85.2
84.7
N.A.
N.A.
76.4
N.A.
68.5
N.A.
N.A.
47.7
N.A.
47.7
P-Site Identity:
100
93.3
86.6
80
N.A.
60
53.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
66.6
73.3
N.A.
N.A.
13.3
N.A.
20
N.A.
N.A.
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
55
0
0
0
10
10
0
0
0
0
% D
% Glu:
10
0
0
10
10
10
0
0
0
0
0
19
0
0
10
% E
% Phe:
46
0
0
10
0
10
10
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
0
19
0
0
10
0
0
73
0
% G
% His:
10
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
19
0
0
0
% I
% Lys:
0
10
46
0
10
0
55
0
10
10
19
0
0
0
0
% K
% Leu:
0
10
19
10
19
0
0
19
64
55
10
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
19
0
0
0
0
0
0
0
0
0
10
10
10
% N
% Pro:
0
0
0
19
0
19
0
0
0
0
10
55
0
0
55
% P
% Gln:
10
0
0
37
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
10
10
10
0
0
0
0
0
0
28
0
0
0
10
% R
% Ser:
10
19
0
10
0
0
0
0
0
10
10
0
19
19
10
% S
% Thr:
0
0
0
0
0
0
10
0
10
10
0
10
0
0
0
% T
% Val:
0
0
0
0
55
10
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
0
0
0
10
55
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _