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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE
All Species:
25.45
Human Site:
Y299
Identified Species:
56
UniProt:
Q9Y251
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y251
NP_001092010.1
543
61177
Y299
S
V
T
W
H
H
Y
Y
L
N
G
R
T
A
T
Chimpanzee
Pan troglodytes
XP_517183
543
61209
Y299
S
V
T
W
H
H
Y
Y
L
N
G
R
T
A
T
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
Y301
S
V
T
W
H
H
Y
Y
L
N
G
R
T
A
T
Dog
Lupus familis
XP_850908
545
61071
Y301
S
V
T
W
H
H
Y
Y
L
N
G
R
I
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
Y291
S
L
T
W
H
H
Y
Y
L
N
G
R
I
A
T
Rat
Rattus norvegicus
Q71RP1
536
60461
Y292
S
L
T
W
H
H
Y
Y
L
N
G
R
V
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
D289
G
R
S
A
T
R
E
D
F
L
S
P
E
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038470
546
60923
Y298
A
C
T
W
H
H
Y
Y
V
N
G
R
D
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121450
528
60132
G289
W
H
Q
Y
Y
L
N
G
K
E
A
Q
L
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
V243
L
L
L
N
I
Q
S
V
Q
N
S
V
K
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
D302
Q
V
S
K
T
F
K
D
V
N
Q
T
I
Q
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95
82.7
N.A.
76.8
75.8
N.A.
N.A.
60.2
N.A.
50.9
N.A.
N.A.
30.3
N.A.
30.3
Protein Similarity:
100
99.2
97.2
89.5
N.A.
85.2
84.7
N.A.
N.A.
76.4
N.A.
68.5
N.A.
N.A.
47.7
N.A.
47.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
60
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
80
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
0
10
0
0
55
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
19
0
0
0
0
10
0
10
% D
% Glu:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
64
0
0
0
0
% G
% His:
0
10
0
0
64
64
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
28
10
0
% I
% Lys:
0
0
0
10
0
0
10
0
10
0
0
0
10
10
0
% K
% Leu:
10
28
10
0
0
10
0
0
55
10
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
82
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
10
0
0
10
0
0
10
0
10
10
0
10
0
% Q
% Arg:
0
10
0
0
0
10
0
0
0
0
0
64
0
0
0
% R
% Ser:
55
0
19
0
0
0
10
0
0
0
19
0
0
0
10
% S
% Thr:
0
0
64
0
19
0
0
0
0
0
0
10
28
10
55
% T
% Val:
0
46
0
0
0
0
0
10
19
0
0
10
10
10
0
% V
% Trp:
10
0
0
64
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
64
64
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _