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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE
All Species:
23.64
Human Site:
T451
Identified Species:
52
UniProt:
Q9Y251
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y251
NP_001092010.1
543
61177
T451
R
Y
K
E
G
D
L
T
L
Y
A
I
N
L
H
Chimpanzee
Pan troglodytes
XP_517183
543
61209
T451
R
Y
K
E
G
D
L
T
L
Y
A
I
N
L
H
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
T453
M
Y
K
E
G
D
L
T
L
Y
A
I
N
L
Y
Dog
Lupus familis
XP_850908
545
61071
T453
R
Y
K
E
G
D
L
T
L
Y
A
L
N
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
T443
R
Y
Q
E
G
D
L
T
L
Y
V
L
N
L
H
Rat
Rattus norvegicus
Q71RP1
536
60461
T444
R
Y
R
E
G
D
L
T
L
Y
V
L
N
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
L437
V
T
L
F
A
L
N
L
S
N
V
T
Q
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038470
546
60923
F454
K
E
G
A
V
T
L
F
A
L
N
L
N
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121450
528
60132
Y437
K
I
V
A
I
T
I
Y
G
I
N
L
Y
K
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
V391
T
F
M
I
I
N
M
V
P
I
N
D
V
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
S453
A
E
S
R
K
K
K
S
L
L
D
T
L
K
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95
82.7
N.A.
76.8
75.8
N.A.
N.A.
60.2
N.A.
50.9
N.A.
N.A.
30.3
N.A.
30.3
Protein Similarity:
100
99.2
97.2
89.5
N.A.
85.2
84.7
N.A.
N.A.
76.4
N.A.
68.5
N.A.
N.A.
47.7
N.A.
47.7
P-Site Identity:
100
100
86.6
93.3
N.A.
80
80
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
33.3
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
19
10
0
0
0
10
0
37
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
55
0
0
0
0
10
10
0
0
0
% D
% Glu:
0
19
0
55
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
55
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
46
% H
% Ile:
0
10
0
10
19
0
10
0
0
19
0
28
0
0
10
% I
% Lys:
19
0
37
0
10
10
10
0
0
0
0
0
0
28
0
% K
% Leu:
0
0
10
0
0
10
64
10
64
19
0
46
10
55
10
% L
% Met:
10
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
10
28
0
64
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
46
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
10
0
0
0
0
10
10
0
0
0
0
10
0
% S
% Thr:
10
10
0
0
0
19
0
55
0
0
0
19
0
0
0
% T
% Val:
10
0
10
0
10
0
0
10
0
0
28
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
55
0
0
0
0
0
10
0
55
0
0
10
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _