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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE
All Species:
18.18
Human Site:
S492
Identified Species:
40
UniProt:
Q9Y251
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y251
NP_001092010.1
543
61177
S492
P
H
G
L
L
S
K
S
V
Q
L
N
G
L
T
Chimpanzee
Pan troglodytes
XP_517183
543
61209
S492
P
H
G
L
L
S
K
S
V
Q
L
N
G
Q
T
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
A494
P
H
G
L
L
S
K
A
V
Q
L
N
G
Q
T
Dog
Lupus familis
XP_850908
545
61071
S494
P
D
E
L
L
S
K
S
V
Q
L
N
G
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
S484
P
D
G
L
L
S
K
S
V
Q
L
N
G
Q
I
Rat
Rattus norvegicus
Q71RP1
536
60461
S485
S
D
G
L
L
S
K
S
V
Q
L
N
G
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
R478
R
E
V
Q
L
N
G
R
L
L
Q
M
V
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038470
546
60923
S495
E
Q
G
L
Y
S
R
S
V
R
L
N
G
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121450
528
60132
K478
N
L
Q
S
R
D
I
K
I
N
G
E
V
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
H432
P
Q
V
D
L
N
G
H
P
L
K
M
D
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
V494
V
L
R
S
K
T
M
V
L
N
G
K
S
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95
82.7
N.A.
76.8
75.8
N.A.
N.A.
60.2
N.A.
50.9
N.A.
N.A.
30.3
N.A.
30.3
Protein Similarity:
100
99.2
97.2
89.5
N.A.
85.2
84.7
N.A.
N.A.
76.4
N.A.
68.5
N.A.
N.A.
47.7
N.A.
47.7
P-Site Identity:
100
93.3
86.6
80
N.A.
80
80
N.A.
N.A.
6.6
N.A.
53.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
80
N.A.
80
80
N.A.
N.A.
20
N.A.
66.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
0
10
0
10
0
0
0
0
0
0
10
19
19
% D
% Glu:
10
10
10
0
0
0
0
0
0
0
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
55
0
0
0
19
0
0
0
19
0
64
0
0
% G
% His:
0
28
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
55
10
0
0
10
10
0
0
19
% K
% Leu:
0
19
0
64
73
0
0
0
19
19
64
0
0
28
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
19
0
0
0
% M
% Asn:
10
0
0
0
0
19
0
0
0
19
0
64
0
0
0
% N
% Pro:
55
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
19
10
10
0
0
0
0
0
55
10
0
0
46
0
% Q
% Arg:
10
0
10
0
10
0
10
10
0
10
0
0
0
0
0
% R
% Ser:
10
0
0
19
0
64
0
55
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
46
% T
% Val:
10
0
19
0
0
0
0
10
64
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _