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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPSE
All Species:
24.85
Human Site:
S228
Identified Species:
54.67
UniProt:
Q9Y251
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y251
NP_001092010.1
543
61177
S228
E
L
G
N
E
P
N
S
F
L
K
K
A
D
I
Chimpanzee
Pan troglodytes
XP_517183
543
61209
S228
E
L
G
N
E
P
N
S
F
L
K
K
A
D
I
Rhesus Macaque
Macaca mulatta
XP_001104975
545
61334
S230
E
L
G
N
E
P
N
S
F
L
K
K
A
D
I
Dog
Lupus familis
XP_850908
545
61071
S230
E
L
G
N
E
P
N
S
F
R
K
K
A
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6YGZ1
535
60032
S220
E
L
G
N
E
P
N
S
F
W
K
K
A
H
I
Rat
Rattus norvegicus
Q71RP1
536
60461
S221
E
L
G
N
E
P
N
S
F
W
K
K
A
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90YK5
523
58368
G218
K
S
G
I
C
I
D
G
F
Q
L
G
R
D
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038470
546
60923
S226
E
L
G
N
E
P
N
S
Y
E
K
K
A
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121450
528
60132
I219
S
F
N
H
V
F
N
I
N
I
T
A
I
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791694
477
53110
L173
P
E
L
T
D
I
F
L
V
G
P
D
T
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF10
543
60232
K229
V
L
K
D
V
I
N
K
V
Y
K
N
S
W
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95
82.7
N.A.
76.8
75.8
N.A.
N.A.
60.2
N.A.
50.9
N.A.
N.A.
30.3
N.A.
30.3
Protein Similarity:
100
99.2
97.2
89.5
N.A.
85.2
84.7
N.A.
N.A.
76.4
N.A.
68.5
N.A.
N.A.
47.7
N.A.
47.7
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
20
N.A.
73.3
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
33.3
N.A.
86.6
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
64
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
10
0
0
0
0
10
0
37
0
% D
% Glu:
64
10
0
0
64
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
10
10
0
64
0
0
0
0
0
10
% F
% Gly:
0
0
73
0
0
0
0
10
0
10
0
10
0
19
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
19
0
% H
% Ile:
0
0
0
10
0
28
0
10
0
10
0
0
10
0
55
% I
% Lys:
10
0
10
0
0
0
0
10
0
0
73
64
0
0
0
% K
% Leu:
0
73
10
0
0
0
0
10
0
28
10
0
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
64
0
0
82
0
10
0
0
10
0
0
0
% N
% Pro:
10
0
0
0
0
64
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
10
10
0
0
0
0
0
64
0
0
0
0
10
10
10
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% T
% Val:
10
0
0
0
19
0
0
0
19
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
19
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _