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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIN4 All Species: 18.72
Human Site: S7 Identified Species: 34.33
UniProt: Q9Y237 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y237 NP_006214.2 131 13810 S7 _ M P P K G K S G S G K A G K
Chimpanzee Pan troglodytes XP_001161176 130 13821 S7 _ M P P K G K S G S G K A G K
Rhesus Macaque Macaca mulatta XP_001092957 164 17481 S40 K M P P K G K S G S G K A G K
Dog Lupus familis XP_849005 131 14135 S7 _ M P P K G K S G S R K R G K
Cat Felis silvestris
Mouse Mus musculus Q9CWW6 131 13796 S7 _ M P P K G K S G S G K G G K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420136 125 13164 G7 _ M A P K G K G G G K A G K G
Frog Xenopus laevis NP_001084775 127 13508 G7 _ M P P K G K G G K G A K G G
Zebra Danio Brachydanio rerio Q503Y7 128 13645 G7 _ M P P K G K G G K G A K G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651364 130 13892 K11 K K D A K S G K D A G K G G K
Honey Bee Apis mellifera XP_001120560 113 12319 K10 N G K E E K K K G N A G N A I
Nematode Worm Caenorhab. elegans NP_496824 126 13302 P7 _ M P P K K T P K G G A S G S
Sea Urchin Strong. purpuratus XP_790053 113 12217 D7 _ G A A G D D D S G G K Q K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RYY4 130 13640 S8 M G K D K K A S G S G S G S K
Conservation
Percent
Protein Identity: 100 94.6 79.2 90 N.A. 96.9 N.A. N.A. N.A. 84.7 87 83.2 N.A. 72.5 61.8 71.7 64.1
Protein Similarity: 100 95.4 79.8 93.8 N.A. 98.4 N.A. N.A. N.A. 90.8 92.3 89.3 N.A. 82.4 73.2 80.1 72.5
P-Site Identity: 100 100 93.3 85.7 N.A. 92.8 N.A. N.A. N.A. 42.8 64.2 64.2 N.A. 33.3 13.3 42.8 21.4
P-Site Similarity: 100 100 93.3 85.7 N.A. 92.8 N.A. N.A. N.A. 42.8 64.2 64.2 N.A. 40 26.6 50 21.4
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 50.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 62.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 40
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 16 0 0 8 0 0 8 8 31 24 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 8 8 8 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 24 0 0 8 62 8 24 77 24 77 8 31 70 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 16 8 16 0 85 24 70 16 8 16 8 54 16 16 62 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 8 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 62 70 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % R
% Ser: 0 0 0 0 0 8 0 47 8 47 0 8 8 8 8 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _