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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIN4 All Species: 17.88
Human Site: S23 Identified Species: 32.78
UniProt: Q9Y237 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y237 NP_006214.2 131 13810 S23 G A A S G S D S A D K K A Q G
Chimpanzee Pan troglodytes XP_001161176 130 13821 S23 G A A S G S D S A D K K A Q G
Rhesus Macaque Macaca mulatta XP_001092957 164 17481 S56 G A A S G S D S A D K K A Q G
Dog Lupus familis XP_849005 131 14135 S23 G A A S R S D S S D K K A Q G
Cat Felis silvestris
Mouse Mus musculus Q9CWW6 131 13796 S23 G A A S G S D S A D K K S Q G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420136 125 13164 Q23 E S G E G K A Q G P K G G G S
Frog Xenopus laevis NP_001084775 127 13508 K23 A S G E A A D K K A Q T P K G
Zebra Danio Brachydanio rerio Q503Y7 128 13645 D23 A S G S G D S D K K E K A Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651364 130 13892 A27 P A A E D K S A G K E K K G G
Honey Bee Apis mellifera XP_001120560 113 12319 L26 S I K V R H I L C E K Q S K I
Nematode Worm Caenorhab. elegans NP_496824 126 13302 K23 K D D G G G Q K K E A K G G G
Sea Urchin Strong. purpuratus XP_790053 113 12217 R23 G T S T V K V R H I L C E K H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RYY4 130 13640 D24 G K D A G N K D A G K D A G K
Conservation
Percent
Protein Identity: 100 94.6 79.2 90 N.A. 96.9 N.A. N.A. N.A. 84.7 87 83.2 N.A. 72.5 61.8 71.7 64.1
Protein Similarity: 100 95.4 79.8 93.8 N.A. 98.4 N.A. N.A. N.A. 90.8 92.3 89.3 N.A. 82.4 73.2 80.1 72.5
P-Site Identity: 100 100 100 86.6 N.A. 93.3 N.A. N.A. N.A. 13.3 13.3 33.3 N.A. 26.6 6.6 20 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 N.A. N.A. N.A. 20 40 46.6 N.A. 40 33.3 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 50.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 62.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 47 47 8 8 8 8 8 39 8 8 0 47 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % C
% Asp: 0 8 16 0 8 8 47 16 0 39 0 8 0 0 0 % D
% Glu: 8 0 0 24 0 0 0 0 0 16 16 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 54 0 24 8 62 8 0 0 16 8 0 8 16 31 62 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 8 % H
% Ile: 0 8 0 0 0 0 8 0 0 8 0 0 0 0 8 % I
% Lys: 8 8 8 0 0 24 8 16 24 16 62 62 8 24 16 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 8 8 0 0 8 8 0 47 0 % Q
% Arg: 0 0 0 0 16 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 8 24 8 47 0 39 16 39 8 0 0 0 16 0 8 % S
% Thr: 0 8 0 8 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 8 8 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _