KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIPT1
All Species:
20.61
Human Site:
T254
Identified Species:
50.37
UniProt:
Q9Y234
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y234
NP_057013.1
373
42479
T254
L
I
N
P
T
D
E
T
L
F
P
G
I
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103668
373
42569
T254
L
I
N
P
T
D
E
T
L
F
P
G
I
N
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCM4
373
42127
T254
L
I
N
P
A
D
E
T
M
F
P
G
I
N
R
Rat
Rattus norvegicus
NP_001101682
371
41918
T254
L
I
N
P
A
D
E
T
V
F
P
G
I
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416893
373
42136
S254
L
I
N
P
T
D
E
S
V
L
P
G
I
N
D
Frog
Xenopus laevis
NP_001087342
354
40473
S253
L
I
D
P
K
D
E
S
L
F
P
G
I
S
Q
Zebra Danio
Brachydanio rerio
NP_001068570
372
41321
A257
T
V
D
P
T
H
E
A
L
M
P
G
I
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611097
396
44086
Q279
G
S
T
Q
T
M
Q
Q
R
G
F
Q
L
V
N
Honey Bee
Apis mellifera
XP_624104
369
42621
Q239
G
Q
D
H
I
Q
Y
Q
K
G
F
Q
Y
I
N
Nematode Worm
Caenorhab. elegans
NP_492468
289
32707
K198
A
P
A
V
G
F
L
K
Q
D
D
A
N
A
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.8
N.A.
N.A.
80.9
80.6
N.A.
N.A.
65.9
57.3
52
N.A.
35.3
38.3
28.1
N.A.
Protein Similarity:
100
N.A.
99.7
N.A.
N.A.
90.8
90.6
N.A.
N.A.
84.4
75.5
71.5
N.A.
55.2
58.1
45
N.A.
P-Site Identity:
100
N.A.
100
N.A.
N.A.
80
86.6
N.A.
N.A.
73.3
66.6
46.6
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
86.6
93.3
N.A.
N.A.
86.6
86.6
66.6
N.A.
26.6
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
20
0
0
10
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
0
0
60
0
0
0
10
10
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
50
20
0
0
0
0
% F
% Gly:
20
0
0
0
10
0
0
0
0
20
0
70
0
0
0
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
60
0
0
10
0
0
0
0
0
0
0
70
10
0
% I
% Lys:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
10
% K
% Leu:
60
0
0
0
0
0
10
0
40
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
50
0
0
0
0
0
0
0
0
0
10
50
30
% N
% Pro:
0
10
0
70
0
0
0
0
0
0
70
0
0
0
0
% P
% Gln:
0
10
0
10
0
10
10
20
10
0
0
20
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% R
% Ser:
0
10
0
0
0
0
0
20
0
0
0
0
0
10
30
% S
% Thr:
10
0
10
0
50
0
0
40
0
0
0
0
0
0
0
% T
% Val:
0
10
0
10
0
0
0
0
20
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _