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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: JAG2 All Species: 22.12
Human Site: S1116 Identified Species: 40.56
UniProt: Q9Y219 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y219 NP_002217.3 1238 133367 S1116 R R K E R E R S R L P R E E S
Chimpanzee Pan troglodytes XP_001169642 1221 134068 H1105 K R R K P G S H T H S A S E D
Rhesus Macaque Macaca mulatta XP_001097477 1062 114676 D970 W G G G G H K D V L Y Q C K N
Dog Lupus familis XP_548004 1098 118057 S970 R R K E R E R S R L P R E E S
Cat Felis silvestris
Mouse Mus musculus Q9QYE5 1247 134709 S1118 R R K E R E R S R L P R D E S
Rat Rattus norvegicus P97607 1202 129686 S1073 R R K E R E R S R L P R D E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520018 1072 115736 V973 L V L F S P L V G S T V K G V
Chicken Gallus gallus XP_001235689 1300 143352 S1179 R R K E R E R S H P P R E E G
Frog Xenopus laevis P21783 2524 275106 N2019 I N A H A D V N A V D E F G K
Zebra Danio Brachydanio rerio Q90Y54 1213 133348 S1099 R R K Q N T H S N T A T S A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18168 1404 150325 G1253 L A Y R T S S G M N L T P S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P14585 1429 157097 T1321 P Q P S R K V T R A P K K Q T
Sea Urchin Strong. purpuratus P10079 1064 112055 M968 G M M L G D Y M T Y N E R A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.7 83.4 67.6 N.A. 89.8 85.8 N.A. 59.2 66.2 21 51.4 N.A. 31.4 N.A. 20.2 27.6
Protein Similarity: 100 68.6 83.7 73.4 N.A. 92.9 89.1 N.A. 67.8 78 30.9 67.2 N.A. 44.5 N.A. 33 40.6
P-Site Identity: 100 13.3 6.6 100 N.A. 93.3 93.3 N.A. 0 80 0 26.6 N.A. 0 N.A. 20 0
P-Site Similarity: 100 33.3 33.3 100 N.A. 100 100 N.A. 6.6 80 20 40 N.A. 0 N.A. 66.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 0 0 0 8 8 8 8 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 16 0 8 0 0 8 0 16 0 8 % D
% Glu: 0 0 0 39 0 39 0 0 0 0 0 16 24 47 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 8 8 8 16 8 0 8 8 0 0 0 0 16 8 % G
% His: 0 0 0 8 0 8 8 8 8 8 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 47 8 0 8 8 0 0 0 0 8 16 8 8 % K
% Leu: 16 0 8 8 0 0 8 0 0 39 8 0 0 0 16 % L
% Met: 0 8 8 0 0 0 0 8 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 8 8 8 8 0 0 0 8 % N
% Pro: 8 0 8 0 8 8 0 0 0 8 47 0 8 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 47 54 8 8 47 0 39 0 39 0 0 39 8 0 0 % R
% Ser: 0 0 0 8 8 8 16 47 0 8 8 0 16 8 31 % S
% Thr: 0 0 0 0 8 8 0 8 16 8 8 16 0 0 16 % T
% Val: 0 8 0 0 0 0 16 8 8 8 0 8 0 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _