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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTMR6 All Species: 19.09
Human Site: Y614 Identified Species: 35
UniProt: Q9Y217 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y217 NP_004676.3 621 71954 Y614 P A V V S L E Y G V A R M T C
Chimpanzee Pan troglodytes XP_509591 621 71935 Y614 P A V V S L E Y G V A R M T C
Rhesus Macaque Macaca mulatta XP_001092084 621 71976 Y614 P A V V S L E Y G V A R M T C
Dog Lupus familis XP_534530 779 88802 Y772 P G V V S L E Y G V A R M T C
Cat Felis silvestris
Mouse Mus musculus Q8VE11 617 70914 Y610 P T V V S L E Y G V A R M T C
Rat Rattus norvegicus Q6AXQ4 602 69333
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519329 1065 118487 C1058 P A I V G L E C G V A R M A C
Chicken Gallus gallus Q5F452 629 71949 D615 L H L N D S V D V L N S E A K
Frog Xenopus laevis Q52KU6 602 69712 M595 P S S P S Q M M P Q V Q T P F
Zebra Danio Brachydanio rerio Q6TEL0 632 72485 K615 H D L S S K D K P V F V E T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611791 689 78732 S606 L S L S A E Q S S P P Q A L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22712 1006 113596 P948 P I K E A E S P S K E T K C P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47147 688 80133 L677 D G G K G L N L S I F G F D M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 76.6 N.A. 89.8 35.4 N.A. 47.5 58.8 36.8 55 N.A. 45.7 N.A. 23.1 N.A.
Protein Similarity: 100 100 99.5 78.4 N.A. 94.8 56.8 N.A. 52.8 75.8 57 73.4 N.A. 64.4 N.A. 38 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 0 N.A. 73.3 0 13.3 20 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 0 N.A. 80 13.3 26.6 33.3 N.A. 33.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 31 0 0 16 0 0 0 0 0 47 0 8 16 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 47 % C
% Asp: 8 8 0 0 8 0 8 8 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 8 0 16 47 0 0 0 8 0 16 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 16 0 8 0 8 % F
% Gly: 0 16 8 0 16 0 0 0 47 0 0 8 0 0 0 % G
% His: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 8 8 0 8 0 8 0 8 0 0 8 0 8 % K
% Leu: 16 0 24 0 0 54 0 8 0 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 8 8 0 0 0 0 47 0 8 % M
% Asn: 0 0 0 8 0 0 8 0 0 0 8 0 0 0 0 % N
% Pro: 62 0 0 8 0 0 0 8 16 8 8 0 0 8 16 % P
% Gln: 0 0 0 0 0 8 8 0 0 8 0 16 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0 % R
% Ser: 0 16 8 16 54 8 8 8 24 0 0 8 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 8 8 47 0 % T
% Val: 0 0 39 47 0 0 8 0 8 54 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 39 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _