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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC3
All Species:
40.3
Human Site:
T603
Identified Species:
63.33
UniProt:
Q9UQE7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQE7
NP_005436.1
1217
141542
T603
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Chimpanzee
Pan troglodytes
XP_508031
1374
158072
T760
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851818
1228
142683
T603
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CW03
1217
141537
T603
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Rat
Rattus norvegicus
P97690
1191
138430
T603
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512851
1238
143475
T624
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Chicken
Gallus gallus
Q90988
1189
134923
H600
L
A
K
N
L
I
G
H
R
E
V
H
I
A
I
Frog
Xenopus laevis
O93309
1209
140704
T603
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Zebra Danio
Brachydanio rerio
NP_999854
1216
141517
T603
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Tiger Blowfish
Takifugu rubipres
NP_001027798
1217
141541
T603
R
D
T
A
Y
P
E
T
N
D
A
I
P
M
I
Fruit Fly
Dros. melanogaster
NP_523374
1200
140018
D604
K
I
H
D
Y
P
D
D
P
D
S
I
P
M
I
Honey Bee
Apis mellifera
XP_393700
1202
139436
T603
K
D
I
D
Y
P
E
T
S
D
A
I
P
M
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202053
792
92535
R261
L
R
T
A
N
E
E
R
D
H
L
T
N
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
K595
V
Q
Q
A
T
V
G
K
G
N
A
E
L
A
L
Baker's Yeast
Sacchar. cerevisiae
P47037
1230
141318
Q611
F
P
S
N
T
T
T
Q
I
Q
F
T
P
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99
N.A.
99.9
97.2
N.A.
97.5
23.3
95.8
95.1
94.9
53.4
55.4
N.A.
40.1
Protein Similarity:
100
88.5
N.A.
99
N.A.
100
97.4
N.A.
98
46.5
97.6
97.5
97.3
73.2
72.9
N.A.
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
6.6
100
100
100
46.6
73.3
N.A.
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
13.3
100
100
100
66.6
86.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
74
0
0
0
0
0
0
74
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
14
0
0
7
7
7
74
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
7
74
0
0
7
0
7
0
7
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
14
0
7
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
7
0
7
0
7
0
0
0
% H
% Ile:
0
7
7
0
0
7
0
0
7
0
0
74
7
0
87
% I
% Lys:
14
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
14
0
0
0
7
0
0
0
0
0
7
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
74
0
% M
% Asn:
0
0
0
14
7
0
0
0
60
7
0
0
7
0
0
% N
% Pro:
0
7
0
0
0
74
0
0
7
0
0
0
80
0
0
% P
% Gln:
0
7
7
0
0
0
0
7
0
7
0
0
0
0
0
% Q
% Arg:
60
7
0
0
0
0
0
7
7
0
0
0
0
0
7
% R
% Ser:
0
0
7
0
0
0
0
0
7
0
7
0
0
0
0
% S
% Thr:
0
0
67
0
14
7
7
67
0
0
0
14
0
0
0
% T
% Val:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
74
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _