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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPG7
All Species:
28.79
Human Site:
Y138
Identified Species:
48.72
UniProt:
Q9UQ90
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ90
NP_003110.1
795
88235
Y138
R
E
R
D
D
Q
M
Y
R
E
R
L
R
T
L
Chimpanzee
Pan troglodytes
XP_001140249
795
88440
Y138
R
E
R
D
D
Q
M
Y
R
E
R
L
R
T
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546777
917
101667
Y262
K
E
R
E
D
Q
M
Y
R
E
R
L
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULF4
781
85978
Y138
K
E
R
E
D
Q
M
Y
R
E
R
L
R
T
L
Rat
Rattus norvegicus
Q7TT47
744
82104
Y138
K
E
R
E
D
Q
M
Y
R
E
R
L
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511408
749
83486
Y100
K
E
R
E
D
Q
M
Y
R
E
R
L
R
T
L
Chicken
Gallus gallus
NP_001012545
768
86064
H108
R
K
R
E
N
Q
M
H
L
E
R
L
R
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923118
788
88169
Y129
R
E
Q
E
D
Q
M
Y
R
E
R
L
R
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_570017
819
90064
F174
T
K
A
V
L
W
L
F
T
I
Y
M
F
V
A
Honey Bee
Apis mellifera
XP_393770
707
80119
L101
Y
Y
S
L
F
S
G
L
V
D
R
F
V
I
I
Nematode Worm
Caenorhab. elegans
NP_500191
747
82795
W111
L
M
E
K
M
K
R
W
L
A
I
S
L
F
A
Sea Urchin
Strong. purpuratus
XP_001202193
915
101037
E251
S
K
K
A
G
D
G
E
N
I
R
M
L
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
Y136
G
D
A
F
S
N
E
Y
Q
N
M
L
I
P
L
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
P173
P
L
N
D
P
S
N
P
V
S
K
N
V
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
N.A.
78.4
N.A.
86.9
82.3
N.A.
80.8
70.5
N.A.
73.9
N.A.
47.8
43.9
43.9
48.2
Protein Similarity:
100
97.3
N.A.
81.7
N.A.
91.4
87.1
N.A.
88.1
83.1
N.A.
84.5
N.A.
64.3
60.3
62.5
62
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
86.6
60
N.A.
86.6
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
86.6
N.A.
100
N.A.
26.6
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.7
39.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.3
56.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
0
0
0
0
0
8
0
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
22
50
8
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
50
8
43
0
0
8
8
0
58
0
0
0
0
0
% E
% Phe:
0
0
0
8
8
0
0
8
0
0
0
8
8
8
0
% F
% Gly:
8
0
0
0
8
0
15
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
8
0
8
15
8
% I
% Lys:
29
22
8
8
0
8
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
8
0
8
8
0
8
8
15
0
0
65
15
0
72
% L
% Met:
0
8
0
0
8
0
58
0
0
0
8
15
0
0
0
% M
% Asn:
0
0
8
0
8
8
8
0
8
8
0
8
0
8
0
% N
% Pro:
8
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
8
0
0
58
0
0
8
0
0
0
0
0
0
% Q
% Arg:
29
0
50
0
0
0
8
0
50
0
72
0
58
0
0
% R
% Ser:
8
0
8
0
8
15
0
0
0
8
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
0
0
0
50
0
% T
% Val:
0
0
0
8
0
0
0
0
15
0
0
0
15
8
8
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
58
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _