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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK11A
All Species:
3.94
Human Site:
S217
Identified Species:
7.22
UniProt:
Q9UQ88
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ88
NP_076916.2
780
90974
S217
Y
S
D
K
V
K
A
S
H
W
S
R
S
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096048
439
49575
Dog
Lupus familis
XP_857026
795
92229
S229
Y
G
D
K
V
K
A
S
H
W
S
R
S
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P24788
784
91495
G229
Y
S
D
K
G
K
V
G
H
W
S
R
S
P
L
Rat
Rattus norvegicus
P46892
436
49529
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026042
772
90216
R226
Y
G
D
K
V
K
M
R
P
W
S
R
S
P
L
Frog
Xenopus laevis
NP_001086696
788
91927
I231
H
S
E
K
N
K
V
I
R
S
R
S
P
I
R
Zebra Danio
Brachydanio rerio
NP_001008646
800
92940
R235
Y
T
D
K
A
R
L
R
H
R
S
R
S
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
A342
L
S
P
T
T
V
A
A
S
V
T
A
G
L
N
Honey Bee
Apis mellifera
XP_625138
840
98674
E222
Y
S
E
T
E
L
M
E
R
P
E
R
S
E
K
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
K163
S
S
E
R
D
S
E
K
H
K
R
H
I
D
R
Sea Urchin
Strong. purpuratus
XP_001200924
927
107857
K289
D
S
D
Q
R
R
S
K
S
S
S
K
A
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
55.2
92.1
N.A.
93.7
50.5
N.A.
N.A.
89
80.4
74.8
N.A.
41.2
46.9
37.8
46.4
Protein Similarity:
100
N.A.
55.7
94.2
N.A.
95.9
52.9
N.A.
N.A.
92.5
87.1
83.7
N.A.
54.2
60.8
55.3
60.7
P-Site Identity:
100
N.A.
0
86.6
N.A.
73.3
0
N.A.
N.A.
66.6
20
46.6
N.A.
13.3
26.6
13.3
20
P-Site Similarity:
100
N.A.
0
86.6
N.A.
73.3
0
N.A.
N.A.
66.6
33.3
60
N.A.
26.6
33.3
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
24
8
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
47
0
8
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
24
0
8
0
8
8
0
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
0
8
0
0
8
0
0
0
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
39
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
47
0
39
0
16
0
8
0
8
0
0
16
% K
% Leu:
8
0
0
0
0
8
8
0
0
0
0
0
0
8
24
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
0
0
0
0
0
8
8
0
0
8
31
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
16
0
16
16
8
16
47
0
8
16
% R
% Ser:
8
54
0
0
0
8
8
16
16
16
47
8
47
8
8
% S
% Thr:
0
8
0
16
8
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
24
8
16
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% W
% Tyr:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _