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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
17.58
Human Site:
S435
Identified Species:
32.22
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S435
D
D
L
L
S
Q
Y
S
L
S
F
T
K
K
T
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S435
D
D
L
L
S
Q
Y
S
L
S
F
M
K
K
T
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S435
D
D
L
L
S
Q
Y
S
L
S
F
T
K
K
T
Dog
Lupus familis
XP_547491
836
92524
S435
D
D
L
L
S
Q
Y
S
L
S
F
T
K
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
A425
R
P
R
N
E
A
L
A
E
D
D
L
L
S
Q
Rat
Rattus norvegicus
NP_001100668
836
91871
S434
D
D
L
L
S
Q
Y
S
S
L
T
K
K
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
Y435
E
D
D
L
L
R
Q
Y
S
F
S
N
T
K
K
Chicken
Gallus gallus
XP_419550
807
90135
G395
P
E
K
S
T
T
K
G
I
E
K
I
I
S
I
Frog
Xenopus laevis
Q9W6K2
734
82213
N358
H
R
S
Q
S
W
D
N
K
Q
L
N
R
K
T
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
K419
P
Q
R
E
S
Q
V
K
R
P
R
E
D
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
N356
K
A
W
P
T
P
K
N
V
K
R
S
K
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
K359
S
F
K
P
E
T
V
K
K
K
L
D
L
P
V
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
Q326
F
V
I
H
R
E
T
Q
K
K
Q
I
V
H
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
0
60
N.A.
20
0
20
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
6.6
60
N.A.
33.3
20
33.3
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
47
8
0
0
0
8
0
0
8
8
8
8
0
0
% D
% Glu:
8
8
0
8
16
8
0
0
8
8
0
8
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
8
31
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
16
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
16
8
8
8
% I
% Lys:
8
0
16
0
0
0
16
16
24
24
8
8
47
47
16
% K
% Leu:
0
0
39
47
8
0
8
0
31
8
16
8
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
16
0
0
0
16
0
0
0
% N
% Pro:
16
8
0
16
0
8
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
8
0
8
0
47
8
8
0
8
8
0
0
0
8
% Q
% Arg:
8
8
16
0
8
8
0
0
8
0
16
0
8
0
8
% R
% Ser:
8
0
8
8
54
0
0
39
16
31
8
8
0
16
8
% S
% Thr:
0
0
0
0
16
16
8
0
0
0
8
24
8
8
39
% T
% Val:
0
8
0
0
0
0
16
0
8
0
0
0
8
0
8
% V
% Trp:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
39
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _