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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM3 All Species: 22.73
Human Site: S769 Identified Species: 38.46
UniProt: Q9UQ16 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ16 NP_001129599.1 869 97746 S769 W I Q H S R R S P P P S P T T
Chimpanzee Pan troglodytes XP_513998 866 97619 S766 W I Q H S R R S P P P S P T T
Rhesus Macaque Macaca mulatta XP_001100178 863 97145 S763 W I Q H S R R S P P P S P T T
Dog Lupus familis XP_850603 854 96173 A754 T A T T F T P A P P P V D D S
Cat Felis silvestris
Mouse Mus musculus Q8BZ98 863 97172 S763 W L Q H S R R S P P P S P T T
Rat Rattus norvegicus Q08877 869 97896 S769 W L Q H S R R S P P P S P T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515097 939 105893 S839 W L Q H S R R S P P P S P T T
Chicken Gallus gallus XP_415501 861 96730 P761 W L Q V Q S V P S G R R S P T
Frog Xenopus laevis NP_001093354 867 97947 G758 W L Q N S N S G H S P T A Q R
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 R594 V A R K L S A R E Q R D C E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 N760 W L P S G L D N P R L S P P S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P39055 830 93389 L733 Y H A C K E A L R I I S E V N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S944 808 89608 V711 T K R E L H N V F I K K L Y R
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 P660 D D L E N A E P P L T E R E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.2 98.3 95 N.A. 96.7 97.1 N.A. 83.8 80.5 79.7 36.2 N.A. 66 N.A. 62.2 N.A.
Protein Similarity: 100 95.5 98.6 95.8 N.A. 98.1 98.6 N.A. 88 88.2 89.3 52.8 N.A. 78.1 N.A. 75.4 N.A.
P-Site Identity: 100 100 100 20 N.A. 93.3 93.3 N.A. 93.3 20 26.6 0 N.A. 26.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 100 100 N.A. 100 26.6 46.6 6.6 N.A. 46.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.5 36 N.A.
Protein Similarity: N.A. N.A. N.A. 52.4 53 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 0 0 8 15 8 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 8 8 0 0 0 0 8 0 0 0 0 8 8 8 0 % D
% Glu: 0 0 0 15 0 8 8 0 8 0 0 8 8 15 8 % E
% Phe: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 8 0 8 0 0 0 0 0 % G
% His: 0 8 0 43 0 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 22 0 0 0 0 0 0 0 15 8 0 0 0 0 % I
% Lys: 0 8 0 8 8 0 0 0 0 0 8 8 0 0 0 % K
% Leu: 0 43 8 0 15 8 0 8 0 8 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 8 8 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 8 0 0 0 8 15 65 50 58 0 50 15 0 % P
% Gln: 0 0 58 0 8 0 0 0 0 8 0 0 0 8 0 % Q
% Arg: 0 0 15 0 0 43 43 8 8 8 15 8 8 0 15 % R
% Ser: 0 0 0 8 50 15 8 43 8 8 0 58 8 0 15 % S
% Thr: 15 0 8 8 0 8 0 0 0 0 8 8 0 43 50 % T
% Val: 8 0 0 8 0 0 8 8 0 0 0 8 0 8 8 % V
% Trp: 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _