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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHDH All Species: 13.33
Human Site: S241 Identified Species: 29.33
UniProt: Q9UQ10 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ10 NP_055290.1 334 36382 S241 L S N T A S V S G T K G M V Q
Chimpanzee Pan troglodytes XP_512808 334 36395 S241 L S N T A S V S G T K G M A Q
Rhesus Macaque Macaca mulatta XP_001112315 408 44331 S241 L S N T A S V S G T K G M A Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9DBB8 333 36282 S241 L P N T A Y V S G T K G M A Q
Rat Rattus norvegicus XP_002725668 333 36244 N241 L P N T A Y V N G T K G M A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DKE0 330 36328 C241 L P N Q T A I C G T K G I I Q
Zebra Danio Brachydanio rerio Q642M9 334 36548 V241 L P N E A L I V G T E G T I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608675 335 37267 K242 L G N T A V I K G T K G Q V T
Honey Bee Apis mellifera XP_623497 331 36880 I241 L P N E A Y I I G T K G M I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786234 350 38766 I241 Y P N D A V I I G T K G H L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SZ83 362 39544 T252 A N L T M E I T A I G T K G T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 77.2 N.A. N.A. 78.7 77.2 N.A. N.A. N.A. 51.7 50.5 N.A. 43.2 41.9 N.A. 39.1
Protein Similarity: 100 97.3 79.1 N.A. N.A. 86.5 86.8 N.A. N.A. N.A. 71.8 68.5 N.A. 60 58.3 N.A. 57.4
P-Site Identity: 100 93.3 93.3 N.A. N.A. 80 73.3 N.A. N.A. N.A. 46.6 40 N.A. 60 53.3 N.A. 40
P-Site Similarity: 100 93.3 93.3 N.A. N.A. 80 80 N.A. N.A. N.A. 73.3 66.6 N.A. 66.6 73.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 23.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 82 10 0 0 10 0 0 0 0 37 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 19 0 10 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 91 0 10 91 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 55 19 0 10 0 0 10 28 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 82 0 10 0 19 % K
% Leu: 82 0 10 0 0 10 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 55 0 0 % M
% Asn: 0 10 91 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 55 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 28 0 0 0 28 0 37 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 64 10 0 0 10 0 91 0 10 10 0 19 % T
% Val: 0 0 0 0 0 19 46 10 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 28 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _