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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
25.76
Human Site:
S525
Identified Species:
51.52
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
S525
P
W
S
S
S
G
L
S
G
K
S
S
G
T
M
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
S526
P
W
S
S
S
G
L
S
G
K
S
S
G
T
M
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
S509
P
W
S
S
S
G
L
S
G
K
S
S
G
T
V
Dog
Lupus familis
XP_538964
685
76968
S578
P
W
S
S
S
G
L
S
G
K
S
S
G
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
S522
S
W
S
S
S
G
L
S
G
K
S
S
G
T
V
Rat
Rattus norvegicus
Q62726
629
70550
S522
S
W
S
S
S
G
L
S
G
K
S
S
G
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
S519
M
F
P
K
P
L
A
S
I
G
A
G
L
S
F
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
F193
I
W
S
L
G
C
I
F
A
E
M
I
T
R
R
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
S525
L
S
G
G
Y
I
P
S
F
Q
K
K
E
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
D465
S
L
S
S
R
N
G
D
S
D
Q
T
K
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
S472
V
A
R
V
G
L
E
S
G
K
S
S
A
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
A338
C
F
L
G
L
T
L
A
V
K
P
S
A
P
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
6.6
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
N.A.
26.6
13.3
N.A.
N.A.
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
9
9
0
9
0
17
0
0
% A
% Cys:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
9
0
0
9
0
0
% E
% Phe:
0
17
0
0
0
0
0
9
9
0
0
0
0
0
9
% F
% Gly:
0
0
9
17
17
50
9
0
59
9
0
9
50
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
9
9
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
67
9
9
9
0
9
% K
% Leu:
9
9
9
9
9
17
59
0
0
0
0
0
9
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
0
9
0
9
0
9
0
0
0
9
0
0
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
0
9
0
9
0
0
0
0
0
0
0
0
9
17
% R
% Ser:
25
9
67
59
50
0
0
75
9
0
59
67
0
17
9
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
9
9
50
0
% T
% Val:
9
0
0
9
0
0
0
0
9
0
0
0
0
9
34
% V
% Trp:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _