KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
23.64
Human Site:
S451
Identified Species:
47.27
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
S451
D
T
L
C
R
F
E
S
V
L
D
L
K
P
S
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
S452
D
T
L
C
R
F
E
S
V
L
D
L
K
P
S
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
S435
D
T
L
C
R
F
E
S
V
L
D
L
K
P
S
Dog
Lupus familis
XP_538964
685
76968
S504
E
T
L
C
R
F
E
S
V
L
D
L
K
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
S448
D
T
L
C
R
F
E
S
V
L
D
L
K
P
S
Rat
Rattus norvegicus
Q62726
629
70550
S448
D
P
L
C
R
F
E
S
V
L
D
L
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
A445
S
D
P
D
P
A
P
A
S
C
N
Q
A
R
G
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
H119
L
Q
G
L
A
F
C
H
S
H
R
V
L
H
R
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
S451
D
S
S
H
Q
S
T
S
S
A
R
Q
H
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
E391
V
N
S
K
L
V
P
E
R
V
Y
K
E
N
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
L398
D
S
W
D
D
F
D
L
E
G
S
R
G
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
A264
L
P
N
A
A
P
E
A
I
D
L
I
N
R
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
100
93.3
N.A.
100
93.3
N.A.
0
N.A.
6.6
13.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
13.3
N.A.
13.3
26.6
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
17
9
0
17
0
9
0
0
9
0
0
% A
% Cys:
0
0
0
50
0
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
59
9
0
17
9
0
9
0
0
9
50
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
59
9
9
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
67
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
9
0
0
9
0
17
% G
% His:
0
0
0
9
0
0
0
9
0
9
0
0
9
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
9
50
0
0
% K
% Leu:
17
0
50
9
9
0
0
9
0
50
9
50
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
0
0
0
0
9
0
9
9
0
% N
% Pro:
0
17
9
0
9
9
17
0
0
0
0
0
0
50
0
% P
% Gln:
0
9
0
0
9
0
0
0
0
0
0
17
0
0
0
% Q
% Arg:
0
0
0
0
50
0
0
0
9
0
17
9
0
17
17
% R
% Ser:
9
17
17
0
0
9
0
59
25
0
9
0
0
0
50
% S
% Thr:
0
42
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
9
0
0
50
9
0
9
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _