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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A11
All Species:
25.76
Human Site:
S356
Identified Species:
47.22
UniProt:
Q9UPY5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY5
NP_055146.1
501
55423
S356
G
H
L
P
E
I
L
S
M
I
H
V
R
K
H
Chimpanzee
Pan troglodytes
XP_001136312
494
54433
S356
G
H
L
P
E
I
L
S
M
I
H
V
R
K
H
Rhesus Macaque
Macaca mulatta
XP_001086173
501
55518
S356
G
H
L
P
E
I
L
S
M
I
H
V
R
K
H
Dog
Lupus familis
XP_540941
488
53551
S356
G
Q
L
P
E
I
L
S
M
I
H
V
R
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTR6
502
55438
S356
G
H
L
P
E
I
L
S
M
I
H
V
H
K
H
Rat
Rattus norvegicus
Q9R0S5
512
55623
C352
G
H
L
P
D
A
I
C
M
I
H
V
E
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520121
442
49024
L311
P
L
P
A
V
I
V
L
H
P
L
T
M
I
M
Chicken
Gallus gallus
XP_426289
516
56714
S354
G
H
L
P
E
I
L
S
M
I
H
V
R
K
H
Frog
Xenopus laevis
A1L3M3
510
55983
C352
G
H
L
P
D
M
L
C
L
I
H
R
E
R
F
Zebra Danio
Brachydanio rerio
Q59I64
468
51216
N335
P
V
P
A
L
L
F
N
C
A
M
A
L
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395404
489
53819
A344
G
H
L
P
A
A
I
A
L
I
N
V
Q
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784464
501
54880
S344
G
H
M
P
A
I
A
S
M
I
H
I
D
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50276
574
63203
S377
R
E
G
V
L
P
F
S
N
F
F
A
S
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.5
92
N.A.
89.2
43.3
N.A.
78.4
81
41.9
44.5
N.A.
N.A.
44.5
N.A.
46.9
Protein Similarity:
100
97.2
99.8
95
N.A.
96.2
65
N.A.
82.4
88.5
65
62.8
N.A.
N.A.
64.2
N.A.
66.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
53.3
N.A.
6.6
100
46.6
0
N.A.
N.A.
40
N.A.
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
73.3
N.A.
13.3
100
73.3
20
N.A.
N.A.
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
16
16
8
8
0
8
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
47
0
0
0
0
0
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
16
0
0
8
8
0
0
0
16
% F
% Gly:
77
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
70
0
0
0
0
0
0
8
0
70
0
8
0
47
% H
% Ile:
0
0
0
0
0
62
16
0
0
77
0
8
0
16
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
16
% K
% Leu:
0
8
70
0
16
8
54
8
16
0
8
0
8
0
8
% L
% Met:
0
0
8
0
0
8
0
0
62
0
8
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
8
0
0
8
0
% N
% Pro:
16
0
16
77
0
8
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
39
24
0
% R
% Ser:
0
0
0
0
0
0
0
62
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
8
0
8
8
0
8
0
0
0
0
62
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _