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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DICER1
All Species:
32.73
Human Site:
Y761
Identified Species:
55.38
UniProt:
Q9UPY3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY3
NP_085124.2
1922
218682
Y761
P
E
C
L
R
D
S
Y
P
R
P
D
Q
P
C
Chimpanzee
Pan troglodytes
XP_001154199
1922
218702
Y761
P
E
C
L
R
D
S
Y
P
R
P
D
Q
P
C
Rhesus Macaque
Macaca mulatta
XP_001100868
1920
218494
Y761
P
E
C
L
R
D
S
Y
P
K
P
D
Q
P
C
Dog
Lupus familis
XP_537547
1923
218622
Y761
P
E
C
L
R
D
S
Y
P
K
P
D
Q
P
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8R418
1916
216802
Y761
P
E
C
L
R
E
S
Y
P
K
P
D
Q
P
C
Rat
Rattus norvegicus
XP_001068155
1918
216871
Y761
P
E
C
L
R
E
S
Y
P
K
P
D
Q
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510982
1921
218622
Y761
P
E
C
L
R
N
S
Y
P
K
P
D
Q
P
C
Chicken
Gallus gallus
Q25BN1
1921
218592
Y761
P
E
C
L
R
D
S
Y
P
K
P
D
Q
P
C
Frog
Xenopus laevis
NP_001163918
1795
204583
L661
P
Y
H
S
T
L
Y
L
P
I
N
S
P
L
R
Zebra Danio
Brachydanio rerio
Q6TV19
1865
210798
S728
S
V
P
G
R
P
G
S
T
K
R
R
Q
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCU9
2249
255312
D965
R
I
A
S
E
F
C
D
C
R
P
V
A
G
A
Honey Bee
Apis mellifera
NP_001116485
1946
224489
D760
K
T
A
E
A
L
T
D
C
R
P
I
I
G
V
Nematode Worm
Caenorhab. elegans
P34529
1845
210905
F678
R
R
K
F
E
D
P
F
N
Y
E
Y
C
F
G
Sea Urchin
Strong. purpuratus
XP_790894
1850
210427
E695
A
Y
I
P
K
N
E
E
G
S
P
R
A
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
97
N.A.
93
93.5
N.A.
91.8
92
76.5
79.2
N.A.
27.7
35.8
31.7
43.5
Protein Similarity:
100
99.9
99.7
98.4
N.A.
96.1
96.4
N.A.
95.8
95.9
83.9
85.5
N.A.
44
54.5
49.6
60.7
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
86.6
93.3
13.3
13.3
N.A.
13.3
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
13.3
20
N.A.
13.3
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
8
0
0
0
0
0
0
0
15
0
8
% A
% Cys:
0
0
58
0
0
0
8
0
15
0
0
0
8
8
58
% C
% Asp:
0
0
0
0
0
43
0
15
0
0
0
58
0
0
0
% D
% Glu:
0
58
0
8
15
15
8
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
8
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
8
0
8
0
0
0
0
15
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
8
0
8
8
0
0
% I
% Lys:
8
0
8
0
8
0
0
0
0
50
0
0
0
0
0
% K
% Leu:
0
0
0
58
0
15
0
8
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
15
0
0
8
0
8
0
0
0
0
% N
% Pro:
65
0
8
8
0
8
8
0
65
0
79
0
8
58
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
65
0
0
% Q
% Arg:
15
8
0
0
65
0
0
0
0
29
8
15
0
0
8
% R
% Ser:
8
0
0
15
0
0
58
8
0
8
0
8
0
8
8
% S
% Thr:
0
8
0
0
8
0
8
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
8
58
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _