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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DICER1
All Species:
14.85
Human Site:
S1618
Identified Species:
25.13
UniProt:
Q9UPY3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY3
NP_085124.2
1922
218682
S1618
N
S
Q
Q
K
N
L
S
V
S
C
A
A
A
S
Chimpanzee
Pan troglodytes
XP_001154199
1922
218702
S1618
N
S
Q
Q
K
N
L
S
V
S
C
A
A
A
S
Rhesus Macaque
Macaca mulatta
XP_001100868
1920
218494
S1616
N
S
Q
Q
K
N
L
S
V
S
C
A
A
A
S
Dog
Lupus familis
XP_537547
1923
218622
S1619
S
S
Q
Q
K
N
L
S
G
G
R
A
A
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R418
1916
216802
A1619
S
L
S
G
S
C
A
A
P
V
G
P
R
S
S
Rat
Rattus norvegicus
XP_001068155
1918
216871
G1617
S
Q
Q
K
S
P
S
G
S
C
A
A
A
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510982
1921
218622
T1618
D
Q
P
R
N
L
L
T
N
Y
A
P
A
S
T
Chicken
Gallus gallus
Q25BN1
1921
218592
P1618
S
E
Q
K
N
L
S
P
N
S
V
S
A
C
I
Frog
Xenopus laevis
NP_001163918
1795
204583
A1513
E
E
N
G
G
A
D
A
G
K
Q
S
I
S
Y
Zebra Danio
Brachydanio rerio
Q6TV19
1865
210798
E1579
Q
S
S
G
G
S
A
E
L
Q
Y
G
W
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCU9
2249
255312
M1853
S
S
V
Q
I
C
E
M
V
R
E
K
A
D
A
Honey Bee
Apis mellifera
NP_001116485
1946
224489
K1641
I
I
Q
E
T
E
P
K
D
R
I
P
G
S
T
Nematode Worm
Caenorhab. elegans
P34529
1845
210905
M1532
P
N
P
T
L
K
V
M
N
W
M
G
L
K
V
Sea Urchin
Strong. purpuratus
XP_790894
1850
210427
D1552
G
Q
S
N
K
R
N
D
Q
S
S
D
L
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
97
N.A.
93
93.5
N.A.
91.8
92
76.5
79.2
N.A.
27.7
35.8
31.7
43.5
Protein Similarity:
100
99.9
99.7
98.4
N.A.
96.1
96.4
N.A.
95.8
95.9
83.9
85.5
N.A.
44
54.5
49.6
60.7
P-Site Identity:
100
100
100
73.3
N.A.
6.6
26.6
N.A.
13.3
20
0
6.6
N.A.
26.6
6.6
0
13.3
P-Site Similarity:
100
100
100
80
N.A.
26.6
40
N.A.
46.6
40
20
20
N.A.
40
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
15
15
0
0
15
36
58
29
15
% A
% Cys:
0
0
0
0
0
15
0
0
0
8
22
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
8
8
8
0
0
8
0
8
0
% D
% Glu:
8
15
0
8
0
8
8
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
22
15
0
0
8
15
8
8
15
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
0
8
0
8
0
8
% I
% Lys:
0
0
0
15
36
8
0
8
0
8
0
8
0
8
8
% K
% Leu:
0
8
0
0
8
15
36
0
8
0
0
0
15
8
0
% L
% Met:
0
0
0
0
0
0
0
15
0
0
8
0
0
0
0
% M
% Asn:
22
8
8
8
15
29
8
0
22
0
0
0
0
0
0
% N
% Pro:
8
0
15
0
0
8
8
8
8
0
0
22
0
8
0
% P
% Gln:
8
22
50
36
0
0
0
0
8
8
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
8
0
0
0
15
8
0
8
0
0
% R
% Ser:
36
43
22
0
15
8
15
29
8
36
8
15
0
29
43
% S
% Thr:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
15
% T
% Val:
0
0
8
0
0
0
8
0
29
8
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _