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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DICER1
All Species:
15.76
Human Site:
S1612
Identified Species:
26.67
UniProt:
Q9UPY3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY3
NP_085124.2
1922
218682
S1612
P
T
R
E
N
F
N
S
Q
Q
K
N
L
S
V
Chimpanzee
Pan troglodytes
XP_001154199
1922
218702
S1612
P
T
R
E
N
F
N
S
Q
Q
K
N
L
S
V
Rhesus Macaque
Macaca mulatta
XP_001100868
1920
218494
S1610
P
T
R
E
N
F
N
S
Q
Q
K
N
L
S
V
Dog
Lupus familis
XP_537547
1923
218622
S1613
P
P
R
E
N
F
S
S
Q
Q
K
N
L
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R418
1916
216802
L1613
G
S
S
Q
Q
K
S
L
S
G
S
C
A
A
P
Rat
Rattus norvegicus
XP_001068155
1918
216871
Q1611
A
Q
E
N
S
S
S
Q
Q
K
S
P
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510982
1921
218622
Q1612
S
T
Q
S
F
N
D
Q
P
R
N
L
L
T
N
Chicken
Gallus gallus
Q25BN1
1921
218592
E1612
T
G
E
N
C
N
S
E
Q
K
N
L
S
P
N
Frog
Xenopus laevis
NP_001163918
1795
204583
E1507
G
F
W
N
P
S
E
E
N
G
G
A
D
A
G
Zebra Danio
Brachydanio rerio
Q6TV19
1865
210798
S1573
V
L
P
P
E
K
Q
S
S
G
G
S
A
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCU9
2249
255312
S1847
L
D
I
K
N
L
S
S
V
Q
I
C
E
M
V
Honey Bee
Apis mellifera
NP_001116485
1946
224489
I1635
P
T
E
E
I
N
I
I
Q
E
T
E
P
K
D
Nematode Worm
Caenorhab. elegans
P34529
1845
210905
N1526
H
L
L
T
L
G
P
N
P
T
L
K
V
M
N
Sea Urchin
Strong. purpuratus
XP_790894
1850
210427
Q1546
V
L
P
T
I
D
G
Q
S
N
K
R
N
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
97
N.A.
93
93.5
N.A.
91.8
92
76.5
79.2
N.A.
27.7
35.8
31.7
43.5
Protein Similarity:
100
99.9
99.7
98.4
N.A.
96.1
96.4
N.A.
95.8
95.9
83.9
85.5
N.A.
44
54.5
49.6
60.7
P-Site Identity:
100
100
100
80
N.A.
0
6.6
N.A.
13.3
6.6
0
6.6
N.A.
26.6
26.6
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
26.6
26.6
N.A.
40
20
6.6
20
N.A.
40
33.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
8
15
15
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
0
8
0
0
0
8
8
0
0
0
0
0
8
8
8
% D
% Glu:
0
0
22
36
8
0
8
15
0
8
0
8
8
8
0
% E
% Phe:
0
8
0
0
8
29
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
8
0
0
0
8
8
0
0
22
15
0
0
8
15
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
15
0
8
8
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
15
0
0
0
15
36
8
0
8
0
% K
% Leu:
8
22
8
0
8
8
0
8
0
0
8
15
36
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% M
% Asn:
0
0
0
22
36
22
22
8
8
8
15
29
8
0
22
% N
% Pro:
36
8
15
8
8
0
8
0
15
0
0
8
8
8
8
% P
% Gln:
0
8
8
8
8
0
8
22
50
36
0
0
0
0
8
% Q
% Arg:
0
0
29
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
8
8
8
8
8
15
36
43
22
0
15
8
15
29
8
% S
% Thr:
8
36
0
15
0
0
0
0
0
8
8
0
0
8
0
% T
% Val:
15
0
0
0
0
0
0
0
8
0
0
0
8
0
29
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _